CAS RN: 1025015-40-0
GK921
Product Availability
Choose a grade to view its available package options.
15 package records13 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250226 | 100mg | In stock | Inquiry | |
| Batchno.20260429 | 10mg | Out of stock | Inquiry | |
| Batchno.20251219 | 1mg | Out of stock | Inquiry | |
| Batchno.20250118 | 200mg | In stock | Inquiry | |
| Batchno.20260204 | 25mg | In stock | Inquiry | |
| Batchno.20260220 | 2mg | In stock | Inquiry | |
| Batchno.20260327 | 50mg | In stock | Inquiry | |
| Batchno.20260407 | 5mg | In stock | Inquiry |
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250624 | 100mg | In stock | Shanghai | Inquiry |
| Batchno.20260206 | 10mg | In stock | Shanghai | Inquiry |
| Batchno.20260305 | 1mg | In stock | Shanghai | Inquiry |
| Batchno.20251118 | 25mg | In stock | Shanghai | Inquiry |
| Batchno.20260304 | 2mg | In stock | Shanghai | Inquiry |
| Batchno.20251202 | 50mg | In stock | Shanghai | Inquiry |
| Batchno.20251119 | 5mg | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS1025015-40-0
- Purity/Analytical Methods: >99.0%
1025015-40-0 / 3-(2-phenylethynyl)-2-(2-pyrrolidin-1-ylethoxy)pyrido[2,3-b]pyrazine
GK921 | 3-(2-phenylethynyl)-2-(2-pyrrolidin-1-ylethoxy)pyrido[2,3-b]pyrazine | 3-(phenylethynyl)-2-(2-(pyrrolidin-1-yl)ethoxy)pyrido[2,3-b]pyrazine
Basic Information
CAS
1025015-40-0
Multi CAS
No
Molecular Formula
C21H20N4O
Molecular Weight
344.400000
Exact Mass
344.163711
SMILES
C1CCN(C1)CCOC2=NC3=C(N=CC=C3)N=C2C#CC4=CC=CC=C4
InChI
InChI=1S/C21H20N4O/c1-2-7-17(8-3-1)10-11-19-21(26-16-15-25-13-4-5-14-25)24-18-9-6-12-22-20(18)23-19/h1-3,6-9,12H,4-5,13-16H2
InChIKey
MNYJJHBAEYKXEG-UHFFFAOYSA-N
Synonyms
GK921
3-(2-phenylethynyl)-2-(2-pyrrolidin-1-ylethoxy)pyrido[2,3-b]pyrazine
3-(phenylethynyl)-2-(2-(pyrrolidin-1-yl)ethoxy)pyrido[2,3-b]pyrazine
1-(2-{[3-(2-phenylethynyl)pyrido[2,3-b]pyrazin-2-yl]oxy}ethyl)pyrrolidine
MFCD28167818
Computed Properties
Structural Parameters
Heavy atom count
26
Aromatic heavy atom count
16
Fraction Csp3
0.29
Rotatable bonds
4
H-bond acceptors
5
Molar refractivity
100.92
TPSA
51.14
LogP / Solubility
WLOGP
2.9
MLOGP
2.57
XLogP3
3.4
Consensus LogP
2.96
Log S (ESOL)
-3.99
Class (ESOL)
Poorly soluble
Log S (Ali)
-4.48
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.79
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.76
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
Yes
Synthetic Accessibility
3
Customers Also Viewed
-
Periglaucine A
- CAS RN: 1025023-04-4
- Product Code: starshine_CAS1025023-04-4
- Purity/Analytical method: >99.0%
-
Periglaucine B
- CAS RN: 1025023-05-5
- Product Code: starshine_CAS1025023-05-5
- Purity/Analytical method: >99.0%
-
BETA-OXO-1-BOC-3-AZETIDINEPROPANOIC ACID ETHYL ESTER
- CAS RN: 1025029-60-0
- Product Code: SSC-003754
-
1-CHLORO-4-[CHLORO(4-CHLOROPHENYL)METHYL]BENZENE
- CAS RN: 1025058-88-1
- Product Code: SSC-003756
-
N-[(BENZYLAMINO)CARBONYL]-2-CHLOROPROPANAMIDE
- CAS RN: 1025058-89-2
- Product Code: SSC-003757
-
![CAS 1025058-88-1 1-CHLORO-4-[CHLORO(4-CHLOROPHENYL)METHYL]BENZENE molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/CB2287520.gif)
![CAS 1025058-89-2 N-[(BENZYLAMINO)CARBONYL]-2-CHLOROPROPANAMIDE molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/CB0410175.gif)
