CAS RN: 1443763-60-7
Mps1-IN-5
Product Availability
Choose a grade to view its available package options.
11 package records10 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250325 | 100mg | Out of stock | Inquiry | |
| Batchno.20250111 | 10mg | In stock | Shanghai | Inquiry |
| Batchno.20260515 | 1mg | In stock | Shanghai | Inquiry |
| Batchno.20250101 | 25mg | In stock | Shanghai | Inquiry |
| Batchno.20251210 | 2mg | In stock | Shanghai | Inquiry |
| Batchno.20250527 | 50mg | In stock | Shanghai | Inquiry |
| Batchno.20250131 | 5mg | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS1443763-60-7
- Purity/Analytical Methods: >99.0%
1443763-60-7 / (2R)-2-(4-fluorophenyl)-N-[4-[2-(2-methoxy-4-methylsulfonylanilino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]phenyl]propanamide
Basic Information
CAS
1443763-60-7
Multi CAS
No
Molecular Formula
C29H26FN5O4S
Molecular Weight
559.600000
Exact Mass
559.168954
SMILES
C[C@H](C1=CC=C(C=C1)F)C(=O)NC2=CC=C(C=C2)C3=CN4C(=NC(=N4)NC5=C(C=C(C=C5)S(=O)(=O)C)OC)C=C3
InChI
InChI=1S/C29H26FN5O4S/c1-18(19-4-9-22(30)10-5-19)28(36)31-23-11-6-20(7-12-23)21-8-15-27-33-29(34-35(27)17-21)32-25-14-13-24(40(3,37)38)16-26(25)39-2/h4-18H,1-3H3,(H,31,36)(H,32,34)/t18-/m1/s1
InChIKey
NRJKIOCCERLIDG-GOSISDBHSA-N
Computed Properties
Structural Parameters
Heavy atom count
40
Aromatic heavy atom count
27
Fraction Csp3
0.14
Rotatable bonds
8
H-bond acceptors
8
H-bond donors
2
Molar refractivity
151.25
TPSA
114.69
LogP / Solubility
WLOGP
5.43
MLOGP
4.82
XLogP3
4.9
Consensus LogP
5.05
Log S (ESOL)
-6.7
Class (ESOL)
Insoluble
Log S (Ali)
-8.07
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-8.77
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.28
Drug-likeness / Medicinal Chemistry
Lipinski
No
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.56
Leadlikeness
No
Synthetic Accessibility
5.5
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