[email protected]
CAS 943540-74-7 JNJ-38877605 molecular structure lightbox
CAS RN: 943540-74-7

JNJ-38877605

Product Availability

Choose a grade to view its available package options.

8 package records7 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20260112 5mg / 10mg / 50mg Out of stock 5-7 business days Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20251231 100mg In stock Shanghai Inquiry
Batchno.20260212 10mg In stock Shanghai Inquiry
Batchno.20250417 1mg In stock Shanghai Inquiry
Batchno.20250619 250mg In stock Shanghai Inquiry
Batchno.20250708 25mg In stock Shanghai Inquiry
Batchno.20250609 50mg In stock Shanghai Inquiry
Batchno.20250610 5mg In stock Shanghai Inquiry
  • Product code: SSC-209069
GET A QUOTE
Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.25g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
Request Bulk Quote

Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 943540-74-7
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.25g ≥95% 0 Out of Stock Hong Kong Inquiry

943540-74-7 / 6-[difluoro-(6-pyridin-4-yl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]quinoline

Standard CAS: 943540-74-7 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
943540-74-7
Multi CAS
No
Molecular Formula
C20F2H12N6
Molecular Weight
374.300000
Exact Mass
374.109151
InChI
InChI=1S/C20H12F2N6/c21-20(22,15-3-4-16-14(12-15)2-1-9-24-16)19-26-25-18-6-5-17(27-28(18)19)13-7-10-23-11-8-13/h1-12H
InChIKey
KOAWAWHSMVKCON-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
28
Aromatic heavy atom count
25
Fraction Csp3
0.05
Rotatable bonds
3
H-bond acceptors
6
Molar refractivity
98.75
TPSA
68.86

LogP / Solubility

WLOGP
3.87
MLOGP
3.43
XLogP3
2.7
Consensus LogP
3.33
Log S (ESOL)
-5.06
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.43
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-5.67
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.25

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5

Customers Also Viewed

Get In Touch

Contact Us