CAS RN: 943319-70-8
Ponatinib
Product Availability
Choose a grade to view its available package options.
7 package records7 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260119 | 100mg | In stock | Shanghai, Tianjin | Inquiry |
| Batchno.20250201 | 1g | In stock | Shanghai | Inquiry |
| Batchno.20250211 | 1mg | In stock | Shanghai | Inquiry |
| Batchno.20260527 | 250mg | In stock | Shanghai, Shenzhen, Wuhan | Inquiry |
| Batchno.20260326 | 5g | In stock | Shanghai, Tianjin | Inquiry |
| Batchno.20260210 | 5mg | In stock | Shanghai | Inquiry |
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260125 | 10mg / 50mg / 250mg / 1g | Confirm by inquiry | Shanghai, Shandong | Inquiry |
- Product code: starshine_CAS943319-70-8
- Purity/Analytical Methods: >99.0%
943319-70-8 / 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
Basic Information
CAS
943319-70-8
Multi CAS
Yes
Molecular Formula
C29F3H27N6O
Molecular Weight
532.600000
Exact Mass
532.219844
InChI
InChI=1S/C29H27F3N6O/c1-20-5-6-22(16-21(20)8-10-25-18-33-27-4-3-11-34-38(25)27)28(39)35-24-9-7-23(26(17-24)29(30,31)32)19-37-14-12-36(2)13-15-37/h3-7,9,11,16-18H,12-15,19H2,1-2H3,(H,35,39)
InChIKey
PHXJVRSECIGDHY-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
39
Aromatic heavy atom count
21
Fraction Csp3
0.28
Rotatable bonds
4
H-bond acceptors
6
H-bond donors
1
Molar refractivity
142.32
TPSA
65.77
LogP / Solubility
WLOGP
4.46
MLOGP
3.96
XLogP3
4.1
Consensus LogP
4.17
Log S (ESOL)
-6.08
Class (ESOL)
Insoluble
Log S (Ali)
-7.14
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.3
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.8
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
5
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