![CAS 942474-71-7 8-[5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]-1,4-DIOXA-8-AZASPIRO[4.5]DECANE molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/CB5805431.gif)
CAS RN: 942474-71-7
8-[5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]-1,4-DIOXA-8-AZASPIRO[4.5]DECANE
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20250606 | 1g / 2g | Out of stock | 15 business days | Inquiry |
- Product code: starshine_CAS942474-71-7
- Purity/Analytical Methods: >99.0%
942474-71-7 / 8-[5-(trifluoromethyl)-2-pyridinyl]-1,4-dioxa-8-azaspiro[4.5]decane
Basic Information
CAS
942474-71-7
Multi CAS
No
Molecular Formula
C13F3H15N2O2
Molecular Weight
288.270000
Exact Mass
288.108562
InChI
InChI=1S/C13H15F3N2O2/c14-13(15,16)10-1-2-11(17-9-10)18-5-3-12(4-6-18)19-7-8-20-12/h1-2,9H,3-8H2
InChIKey
RGZZGINKRRDSSS-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
20
Aromatic heavy atom count
6
Fraction Csp3
0.62
Rotatable bonds
1
H-bond acceptors
4
Molar refractivity
65.32
TPSA
34.59
LogP / Solubility
WLOGP
2.44
MLOGP
2.16
XLogP3
2.1
Consensus LogP
2.23
Log S (ESOL)
-3.32
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.69
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.68
Class (SILICOS-IT)
Poorly soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.74
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
Yes
Synthetic Accessibility
2.5
Customers Also Viewed
-
![CAS 942474-81-9 8-[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]-1,4-DIOXA-8-AZASPIRO-[4,5]-DECANE molecular structure](data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%200%200'%3E%3C/svg%3E)
8-[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]-1,4-DIOXA-8-AZASPIRO-[4,5]-DECANE
- CAS RN: 942474-81-9
- Product Code: starshine_CAS942474-81-9
- Purity/Analytical method: >99.0%
-
-
Nemoralisin
- CAS RN: 942480-13-9
- Product Code: starshine_CAS942480-13-9
- Purity/Analytical method: >99.0%
-
-
PF-03814735
- CAS RN: 942487-16-3
- Product Code: starshine_CAS942487-16-3
- Purity/Analytical method: >99.0%
-
RAC-6-NITRO-1,2,3,4-TETRAHYDRO-1,4-EPIAZANO-NAPHTHALENE-9-CARBOXYLIC ACID TERT-BUTYL ESTER
- CAS RN: 942492-08-2
- Product Code: SSC-208907
![CAS 942474-81-9 8-[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]-1,4-DIOXA-8-AZASPIRO-[4,5]-DECANE molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/CB4820293.gif)
![CAS 942485-62-3 4-[[(4-Fluorophenyl)Imino]Methyl]-Phenol molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/942485-62-3.gif)
