[email protected]
CAS 941294-43-5 4-Chloro-6-(cyclopropylamino)pyrimidine molecular structure lightbox
CAS RN: 941294-43-5

4-Chloro-6-(cyclopropylamino)pyrimidine

Product Availability

Choose a grade to view its available package options.

1 package records1 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250623 250mg / 1g Confirm by inquiry Shanghai Inquiry
  • Product code: starshine_CAS941294-43-5
  • Purity/Analytical Methods: >99.0%
GET A QUOTE

941294-43-5 / 6-chloro-N-cyclopropylpyrimidin-4-amine

Standard CAS: 941294-43-5 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
941294-43-5
Multi CAS
No
Molecular Formula
C7H8CLN3
Molecular Weight
169.610000
Exact Mass
169.040675
InChI
InChI=1S/C7H8ClN3/c8-6-3-7(10-4-9-6)11-5-1-2-5/h3-5H,1-2H2,(H,9,10,11)
InChIKey
ZFIQMVQXKPRCGZ-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
11
Aromatic heavy atom count
6
Fraction Csp3
0.43
Rotatable bonds
2
H-bond acceptors
3
H-bond donors
1
Molar refractivity
43.69
TPSA
37.81

LogP / Solubility

WLOGP
1.7
MLOGP
1.5
XLogP3
2
Consensus LogP
1.73
Log S (ESOL)
-2.24
Class (ESOL)
Moderately soluble
Log S (Ali)
-2.18
Class (Ali)
Moderately soluble
Log S (SILICOS-IT)
-2.42
Class (SILICOS-IT)
Moderately soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.54

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5

Customers Also Viewed

Get In Touch

Contact Us