CAS RN: 915942-22-2
Neratinib Maleate
Product Availability
Choose a grade to view its available package options.
6 package records6 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250902 | 100mg | In stock | Shanghai | Inquiry |
| Batchno.20250513 | 1g | In stock | Shanghai | Inquiry |
| Batchno.20260527 | 1mg | In stock | Shanghai, Tianjin, Wuhan | Inquiry |
| Batchno.20250615 | 200mg / 1g / 5g | Confirm by inquiry | Shanghai, Shandong | Inquiry |
| Batchno.20250914 | 250mg | In stock | Shanghai | Inquiry |
| Batchno.20250627 | 5g | In stock | Tianjin, Chengdu | Inquiry |
- Product code: SSC-204874
Historical Factory Record
Historical Supply Reference
This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
- Pack sizes on record: 1g
- Available purity: ≥95%
- Inventory rows with stock: 0
- Bulk packaging: confirmed by inquiry
Reference Pack Sizes
Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.
| Pack Size | Recorded Purity | Available Qty | Ship From | Inquiry |
|---|---|---|---|---|
| 1g | ≥95% | 0 Out of Stock | Shanghai | Inquiry |
915942-22-2 / (Z)-but-2-enedioic acid;(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
Basic Information
CAS
915942-22-2
Multi CAS
Yes
Molecular Formula
C34H33CLN6O7
Molecular Weight
673.100000
Exact Mass
672.209925
InChI
InChI=1S/C30H29ClN6O3.C4H4O4/c1-4-39-28-16-25-23(15-26(28)36-29(38)9-7-13-37(2)3)30(20(17-32)18-34-25)35-21-10-11-27(24(31)14-21)40-19-22-8-5-6-12-33-22;5-3(6)1-2-4(7)8/h5-12,14-16,18H,4,13,19H2,1-3H3,(H,34,35)(H,36,38);1-2H,(H,5,6)(H,7,8)/b9-7+;2-1-
InChIKey
VXZCUHNJXSIJIM-MEBGWEOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
48
Aromatic heavy atom count
22
Fraction Csp3
0.18
Rotatable bonds
13
H-bond acceptors
10
H-bond donors
4
Molar refractivity
181.67
TPSA
187
LogP / Solubility
WLOGP
5.64
MLOGP
5.02
XLogP3
5.64
Consensus LogP
5.43
Log S (ESOL)
-7.05
Class (ESOL)
Insoluble
Log S (Ali)
-9.15
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-10.28
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.82
Drug-likeness / Medicinal Chemistry
Lipinski
No
Ghose
No
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.17
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
4.5
