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CAS 873054-44-5 Ivacaftor molecular structure lightbox
CAS RN: 873054-44-5

Ivacaftor

Product Availability

Choose a grade to view its available package options.

10 package records10 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250131 100g In stock Shanghai Inquiry
Batchno.20250208 100mg In stock Shanghai Inquiry
Batchno.20260607 10mg In stock Shanghai, Tianjin Inquiry
Batchno.20250308 1g In stock Shanghai, Shenzhen Inquiry
Batchno.20250614 1mg In stock Shanghai, Tianjin Inquiry
Batchno.20250304 250mg In stock Shanghai Inquiry
Batchno.20250305 25g In stock Shanghai Inquiry
Batchno.20260123 5g In stock Shanghai, Shenzhen Inquiry
Batchno.20250730 5mg In stock Shanghai Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250926 10mg / 50mg / 250mg / 1g / 5g Confirm by inquiry Shanghai, Guangdong, Shandong, Hebei 5-7 business days Inquiry
  • Product code: SSC-197114
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Verified Factory Data

Supply Overview & Packaging Options

Packaging options, recorded purity, stock quantity and ship-from location below are generated from the current factory data table for this CAS.

  • Pack sizes on record: 0.1g, 0.25g, 1g
  • Available purity: >97%
  • Inventory rows with stock: 6
  • Bulk packaging: confirmed by inquiry
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Available Pack Sizes & Stock

Specific stock quantities are shown below. Price is not displayed online and is confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 873054-44-5
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.1g -- 1 In Stock Shenzhen Inquiry
0.1g >97% 1 In Stock Hong Kong Inquiry
0.25g -- 1 In Stock Beijing Inquiry
0.25g >97% 1 In Stock Hong Kong Inquiry
1g -- 1 In Stock Shenzhen Inquiry
1g >97% 1 In Stock Beijing Inquiry

873054-44-5 / N-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide

Standard CAS: 873054-44-5 Multi CAS: Yes
Basic Information Physical Properties Computed Properties

Basic Information

CAS
873054-44-5
Multi CAS
Yes
Molecular Formula
C24H28N2O3
Molecular Weight
392.500000
Exact Mass
392.209993
InChI
InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29)
InChIKey
PURKAOJPTOLRMP-UHFFFAOYSA-N

Physical Properties

Melting Point
212-215
Physical Description
Solid
State
Solid

Computed Properties

Structural Parameters

Heavy atom count
29
Aromatic heavy atom count
16
Fraction Csp3
0.33
Rotatable bonds
2
H-bond acceptors
3
H-bond donors
3
Molar refractivity
118.03
TPSA
82.19

LogP / Solubility

WLOGP
5.08
MLOGP
4.49
XLogP3
5.6
Consensus LogP
5.06
Log S (ESOL)
-5.75
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.45
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-6.67
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.51

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
2.5

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