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CAS 850140-73-7 BIBW2992 DiMaleate molecular structure lightbox
CAS RN: 850140-73-7

BIBW2992 DiMaleate

Product Availability

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15 package records15 with current stock4 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260112 1g In stock Inquiry
Batchno.20250615 250mg In stock Inquiry
Batchno.20251101 5g In stock Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250905 1ml In stock Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250321 100g In stock Shenzhen Inquiry
Batchno.20250629 100mg In stock Shanghai Inquiry
Batchno.20250513 10mg In stock Shanghai Inquiry
Batchno.20250304 1g In stock Shanghai, Shenzhen, Tianjin, Wuhan Inquiry
Batchno.20250730 1mg In stock Shanghai Inquiry
Batchno.20251019 250mg In stock Shanghai, Shenzhen, Tianjin, Wuhan, Chengdu Inquiry
Batchno.20250204 25g In stock Shanghai Inquiry
Batchno.20260619 25mg / 100mg / 500mg / 1g / 5g / 25g Confirm by inquiry Shanghai, Shandong Inquiry
Batchno.20250501 50mg In stock Shanghai Inquiry
Batchno.20260126 5g In stock Shanghai Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250722 25mg In stock Shanghai Inquiry
  • Product code: SSC-192880
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 1g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 850140-73-7
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g ≥95% 0 Out of Stock Beijing Inquiry

850140-73-7 / (Z)-but-2-enedioic acid;(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Standard CAS: 850140-73-7 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
850140-73-7
Multi CAS
Yes
Molecular Formula
C28H29CLFN5O7
Molecular Weight
602.000000
Exact Mass
601.173954
InChI
InChI=1S/C24H25ClFN5O3.C4H4O4/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15;5-3(6)1-2-4(7)8/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29);1-2H,(H,5,6)(H,7,8)/b4-3+;2-1-/t16-;/m0./s1
InChIKey
LIENDGDDWJRJLO-WFFUCRSMSA-N

Computed Properties

Structural Parameters

Heavy atom count
42
Aromatic heavy atom count
16
Fraction Csp3
0.25
Rotatable bonds
10
H-bond acceptors
9
H-bond donors
4
Molar refractivity
154.82
TPSA
163.21

LogP / Solubility

WLOGP
4.1
MLOGP
3.66
XLogP3
4.1
Consensus LogP
3.95
Log S (ESOL)
-5.78
Class (ESOL)
Slightly soluble
Log S (Ali)
-7.46
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-8.18
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.48

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
5

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