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CAS 755037-03-7 Regorafenib molecular structure lightbox
CAS RN: 755037-03-7

Regorafenib

Product Availability

Choose a grade to view its available package options.

8 package records8 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20251012 10mg In stock Shanghai Inquiry
Batchno.20250724 10mg / 50mg / 100mg / 250mg / 500mg / 1g / 5g Confirm by inquiry Shanghai, Shandong, Hebei, Chongqing, Guangdong Inquiry
Batchno.20260329 1g In stock Shanghai, Shenzhen, Tianjin Inquiry
Batchno.20260128 1mg In stock Shanghai Inquiry
Batchno.20250322 250mg In stock Shanghai, Shenzhen, Tianjin Inquiry
Batchno.20250204 25g In stock Tianjin Inquiry
Batchno.20250529 5g In stock Shanghai, Shenzhen, Tianjin, Wuhan, Chengdu Inquiry
Batchno.20250801 5mg In stock Shanghai Inquiry
  • Product code: SSC-184970
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 1g
  • Available purity: ≥98%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 755037-03-7
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g ≥98% 0 Out of Stock Beijing Inquiry

755037-03-7 / 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide

Standard CAS: 755037-03-7 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
755037-03-7
Multi CAS
Yes
Molecular Formula
C21H15CLF4N4O3
Molecular Weight
482.800000
Exact Mass
482.076881
InChI
InChI=1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32)
InChIKey
FNHKPVJBJVTLMP-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
33
Aromatic heavy atom count
18
Fraction Csp3
0.1
Rotatable bonds
5
H-bond acceptors
4
H-bond donors
3
Molar refractivity
113.2
TPSA
92.35

LogP / Solubility

WLOGP
5.69
MLOGP
5.04
XLogP3
4.2
Consensus LogP
4.98
Log S (ESOL)
-6.49
Class (ESOL)
Insoluble
Log S (Ali)
-7.63
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-8.12
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.63

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
2.5

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