CAS RN: 65184-10-3
teoprolol
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20250331 | 1mg / 5mg | Out of stock | 15 business days | Inquiry |
- Product code: starshine_CAS65184-10-3
- Purity/Analytical Methods: >99.0%
65184-10-3 / 7-[3-[[2-hydroxy-3-[(2-methyl-1H-indol-4-yl)oxy]propyl]amino]butyl]-1,3-dimethylpurine-2,6-dione
Basic Information
CAS
65184-10-3
Multi CAS
Yes
Molecular Formula
C23H30N6O4
Molecular Weight
454.500000
Exact Mass
454.232853
InChI
InChI=1S/C23H30N6O4/c1-14(8-9-29-13-25-21-20(29)22(31)28(4)23(32)27(21)3)24-11-16(30)12-33-19-7-5-6-18-17(19)10-15(2)26-18/h5-7,10,13-14,16,24,26,30H,8-9,11-12H2,1-4H3
InChIKey
HITMZSXZYGLDCV-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
33
Aromatic heavy atom count
18
Fraction Csp3
0.43
Rotatable bonds
9
H-bond acceptors
9
H-bond donors
3
Molar refractivity
126.83
TPSA
119.1
LogP / Solubility
WLOGP
1.03
MLOGP
0.94
XLogP3
1.4
Consensus LogP
1.12
Log S (ESOL)
-3.12
Class (ESOL)
Poorly soluble
Log S (Ali)
-4.03
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.55
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-4.76
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
4
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- Product Code: starshine_CAS65189-71-1
- Purity/Analytical method: >99.0%
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