CAS RN: 380843-75-4
Bosutinib
Product Availability
Choose a grade to view its available package options.
7 package records7 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250904 | 100mg | In stock | Shanghai, Shenzhen, Tianjin, Wuhan, Chengdu | Inquiry |
| Batchno.20260520 | 10g | In stock | Shanghai | Inquiry |
| Batchno.20250404 | 10mg | In stock | Shanghai | Inquiry |
| Batchno.20250318 | 1g | In stock | Shanghai, Tianjin, Chengdu | Inquiry |
| Batchno.20260604 | 1mg | In stock | Shanghai | Inquiry |
| Batchno.20250512 | 250mg | In stock | Shanghai, Tianjin, Wuhan, Chengdu | Inquiry |
| Batchno.20251211 | 5g | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS380843-75-4
- Purity/Analytical Methods: >99.0%
380843-75-4 / 4-(2,4-dichloro-5-methoxyanilino)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile
Basic Information
CAS
380843-75-4
Multi CAS
Yes
Molecular Formula
C26H29CL2N5O3
Molecular Weight
530.400000
Exact Mass
529.164745
InChI
InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)
InChIKey
UBPYILGKFZZVDX-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
36
Aromatic heavy atom count
16
Fraction Csp3
0.38
Rotatable bonds
9
H-bond acceptors
8
H-bond donors
1
Molar refractivity
143.36
TPSA
82.88
LogP / Solubility
WLOGP
5.19
MLOGP
4.61
XLogP3
5.4
Consensus LogP
5.07
Log S (ESOL)
-6.13
Class (ESOL)
Insoluble
Log S (Ali)
-7.66
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-8.5
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.27
Drug-likeness / Medicinal Chemistry
Lipinski
No
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.56
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
4.5
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