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CAS RN: 371934-59-7
PIK-inhibitors
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20250909 | 5mg | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS371934-59-7
- Purity/Analytical Methods: >99.0%
371934-59-7 / 3-(6-morpholin-4-yl-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl)aniline
Basic Information
CAS
371934-59-7
Multi CAS
No
Molecular Formula
C19H17N5O2
Molecular Weight
347.400000
Exact Mass
347.138225
InChI
InChI=1S/C19H17N5O2/c20-13-4-1-3-12(11-13)17-22-15-14-5-2-6-21-19(14)26-16(15)18(23-17)24-7-9-25-10-8-24/h1-6,11H,7-10,20H2
InChIKey
RQPKSOWRJPRYCN-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
26
Aromatic heavy atom count
19
Fraction Csp3
0.21
Rotatable bonds
2
H-bond acceptors
7
H-bond donors
1
Molar refractivity
99.99
TPSA
90.3
LogP / Solubility
WLOGP
2.86
MLOGP
2.53
XLogP3
2.4
Consensus LogP
2.6
Log S (ESOL)
-4.2
Class (ESOL)
Slightly soluble
Log S (Ali)
-4.47
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.53
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.81
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
Yes
Synthetic Accessibility
3.5
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![CAS 371942-69-7 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3′,2′:4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/371942-69-7(2).gif)
![CAS 371945-06-1 Furo[2,3-b]pyridine-2-carboxylic acid, 3-amino-, ethyl ester (9CI) molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/371945-06-1(2).gif)
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