![CAS 2640567-43-5 4-Piperidinol, 4-(aminomethyl)-1-[5-[2-methoxy-6-(1-methylethyl)-3-pyridinyl]imidazo[2,1-b]-1,3,4-thiadiazol-2-yl]- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/2640567-43-5.gif)
CAS RN: 2640567-43-5
4-Piperidinol, 4-(aminomethyl)-1-[5-[2-methoxy-6-(1-methylethyl)-3-pyridinyl]imidazo[2,1-b]-1,3,4-thiadiazol-2-yl]-
Product Availability
Choose a grade to view its available package options.
6 package records3 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20260520 | 100mg | Out of stock | Inquiry | ||
| Batchno.20260623 | 10mg | In stock | Shanghai | Inquiry | |
| Batchno.20250421 | 10mg / 25mg | Out of stock | 8-10 business days | Inquiry | |
| Batchno.20250320 | 250mg | Out of stock | Inquiry | ||
| Batchno.20260209 | 25mg | In stock | Shanghai | Inquiry | |
| Batchno.20251202 | 50mg | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS2640567-43-5
- Purity/Analytical Methods: >99.0%
2640567-43-5 / 4-(aminomethyl)-1-[5-(2-methoxy-6-propan-2-yl-3-pyridinyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidin-4-ol
Basic Information
CAS
2640567-43-5
Multi CAS
No
Molecular Formula
C19H26N6O2S
Molecular Weight
402.500000
Exact Mass
402.183795
SMILES
CC(C)C1=NC(=C(C=C1)C2=CN=C3N2N=C(S3)N4CCC(CC4)(CN)O)OC
InChI
InChI=1S/C19H26N6O2S/c1-12(2)14-5-4-13(16(22-14)27-3)15-10-21-17-25(15)23-18(28-17)24-8-6-19(26,11-20)7-9-24/h4-5,10,12,26H,6-9,11,20H2,1-3H3
InChIKey
JYHSRMKXBAPFST-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
28
Aromatic heavy atom count
14
Fraction Csp3
0.53
Rotatable bonds
5
H-bond acceptors
9
H-bond donors
2
Molar refractivity
110.19
TPSA
101.8
LogP / Solubility
WLOGP
2.27
MLOGP
2.03
XLogP3
2.1
Consensus LogP
2.13
Log S (ESOL)
-3.81
Class (ESOL)
Poorly soluble
Log S (Ali)
-4.5
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.76
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.56
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3
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