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CAS 2378173-15-8 PF-06928215 molecular structure lightbox
CAS RN: 2378173-15-8

PF-06928215

Product Availability

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8 package records6 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20260117 1mg / 5mg / 25mg / 100mg / 250mg Out of stock 5-7 business days Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20260614 100mg In stock Tianjin Inquiry
Batchno.20260503 10mg In stock Shanghai Inquiry
Batchno.20250302 1mg In stock Shanghai Inquiry
Batchno.20250413 250mg Out of stock Inquiry
Batchno.20260114 25mg In stock Shanghai Inquiry
Batchno.20250324 50mg In stock Shanghai Inquiry
Batchno.20251103 5mg In stock Shanghai Inquiry
  • Product code: SSC-115751
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.1g
  • Available purity: >98%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 2378173-15-8
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.1g >98% 0 Out of Stock Shanghai Inquiry

2378173-15-8 / cis-(1R,2S)-2-[(7-oxo-5-phenyl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]cyclohexane-1-carboxylic acid

Standard CAS: 2378173-15-8 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
2378173-15-8
Multi CAS
No
Molecular Formula
C20H20N4O4
Molecular Weight
380.400000
Exact Mass
380.148455
SMILES
C1CC[C@@H]([C@@H](C1)C(=O)O)NC(=O)C2=CNN3C2=NC(=CC3=O)C4=CC=CC=C4
InChI
InChI=1S/C20H20N4O4/c25-17-10-16(12-6-2-1-3-7-12)22-18-14(11-21-24(17)18)19(26)23-15-9-5-4-8-13(15)20(27)28/h1-3,6-7,10-11,13,15,21H,4-5,8-9H2,(H,23,26)(H,27,28)/t13-,15+/m1/s1
InChIKey
WGQGCLHXUPGUSZ-HIFRSBDPSA-N

Computed Properties

Structural Parameters

Heavy atom count
28
Aromatic heavy atom count
15
Fraction Csp3
0.3
Rotatable bonds
4
H-bond acceptors
5
H-bond donors
3
Molar refractivity
102.1
TPSA
116.56

LogP / Solubility

WLOGP
2.06
MLOGP
1.84
XLogP3
2.3
Consensus LogP
2.07
Log S (ESOL)
-3.63
Class (ESOL)
Poorly soluble
Log S (Ali)
-4.17
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.32
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.58

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
4

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