![CAS 2377355-48-9 Spiro[6H-cyclopenta[b]pyridine-6,4′-piperidin]-5-amine, 5,7-dihydro-, hydrochloride (1:2), (5S)- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/2377355-48-9.gif)
CAS RN: 2377355-48-9
Spiro[6H-cyclopenta[b]pyridine-6,4′-piperidin]-5-amine, 5,7-dihydro-, hydrochloride (1:2), (5S)-
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20251207 | 100mg | Out of stock | 15 business days | Inquiry |
- Product code: SSC-115646
Historical Factory Record
Historical Supply Reference
This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
- Pack sizes on record: 0.25g
- Available purity: ≥95%
- Inventory rows with stock: 0
- Bulk packaging: confirmed by inquiry
Reference Pack Sizes
Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.
| Pack Size | Recorded Purity | Available Qty | Ship From | Inquiry |
|---|---|---|---|---|
| 0.25g | ≥95% | 0 Out of Stock | Hong Kong | Inquiry |
2377355-48-9 / (5S)-spiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-5-amine;dihydrochloride
Basic Information
CAS
2377355-48-9
Multi CAS
No
Molecular Formula
C12H19Cl2N3
Molecular Weight
276.200000
Exact Mass
275.095603
SMILES
C1CNCCC12CC3=C([C@H]2N)C=CC=N3.Cl.Cl
InChI
InChI=1S/C12H17N3.2ClH/c13-11-9-2-1-5-15-10(9)8-12(11)3-6-14-7-4-12;;/h1-2,5,11,14H,3-4,6-8,13H2;2*1H/t11-;;/m1../s1
InChIKey
MEXYAOMAYUHEQW-NVJADKKVSA-N
Computed Properties
Structural Parameters
Heavy atom count
17
Aromatic heavy atom count
6
Fraction Csp3
0.58
H-bond acceptors
3
H-bond donors
2
Molar refractivity
73.9
TPSA
50.94
LogP / Solubility
WLOGP
1.85
MLOGP
1.64
XLogP3
1.85
Consensus LogP
1.78
Log S (ESOL)
-2.98
Class (ESOL)
Moderately soluble
Log S (Ali)
-3.16
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-2.99
Class (SILICOS-IT)
Moderately soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.09
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
Yes
Synthetic Accessibility
3
Customers Also Viewed
-
-
MRGPRX1 agonist 1
- CAS RN: 2377379-39-8
- Product Code: starshine_CAS2377379-39-8
- Purity/Analytical method: >99.0%
-
-
Pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-chlorophenyl)-6-(2-methyl-2H-indazol-5-yl)-2-[(2,2,2-trifluoroethyl)amino]-
- CAS RN: 2377491-54-6
- Product Code: SSC-115663
-
Benzamide, N-[5-(3,5-dicyano-1,4-dihydro-1,2,6-trimethyl-4-pyridinyl)-6-fluoro-7-methyl-1H-indazol-3-yl]-2-ethyl-
- CAS RN: 2377576-35-5
- Product Code: SSC-115665
-
![CAS 2377491-54-6 Pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-chlorophenyl)-6-(2-methyl-2H-indazol-5-yl)-2-[(2,2,2-trifluoroethyl)amino]- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/2377491-54-6.gif)
![CAS 2377576-35-5 Benzamide, N-[5-(3,5-dicyano-1,4-dihydro-1,2,6-trimethyl-4-pyridinyl)-6-fluoro-7-methyl-1H-indazol-3-yl]-2-ethyl- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/2377576-35-5.gif)
