![CAS 2374856-75-2 (5S,5’S)-5,5′-((((5,5′-(2,2′-dichloro-[1,1′-biphenyl]-3,3′-diyl)bis(3-methoxypyrazine-5,2-diyl))bis(methylene))bis(azanediyl))bis(methylene))bis(pyrrolidin-2-one) molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/2374856-75-2.gif)
CAS RN: 2374856-75-2
(5S,5’S)-5,5′-((((5,5′-(2,2′-dichloro-[1,1′-biphenyl]-3,3′-diyl)bis(3-methoxypyrazine-5,2-diyl))bis(methylene))bis(azanediyl))bis(methylene))bis(pyrrolidin-2-one)
Product Availability
Choose a grade to view its available package options.
14 package records13 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20260413 | 100mg | In stock | Shanghai | Inquiry | |
| Batchno.20251108 | 10mg | In stock | Shanghai | Inquiry | |
| Batchno.20260430 | 1mg | In stock | Shanghai | Inquiry | |
| Batchno.20250811 | 250mg | In stock | Shanghai | Inquiry | |
| Batchno.20250713 | 25mg | In stock | Shanghai | Inquiry | |
| Batchno.20260405 | 50mg | In stock | Shanghai | Inquiry | |
| Batchno.20250510 | 5mg | In stock | Shanghai | Inquiry | |
| Batchno.20250427 | 5mg / 25mg / 100mg | Out of stock | 8-10 business days | Inquiry |
- Product code: starshine_CAS2374856-75-2
- Purity/Analytical Methods: >99.0%
2374856-75-2 / (5S)-5-[[[5-[2-chloro-3-[2-chloro-3-[6-methoxy-5-[[[(2S)-5-oxopyrrolidin-2-yl]methylamino]methyl]pyrazin-2-yl]phenyl]phenyl]-3-methoxypyrazin-2-yl]methylamino]methyl]pyrrolidin-2-one
Basic Information
CAS
2374856-75-2
Multi CAS
No
Molecular Formula
C34H36Cl2N8O4
Molecular Weight
691.600000
Exact Mass
690.223657
SMILES
COC1=NC(=CN=C1CNC[C@@H]2CCC(=O)N2)C3=CC=CC(=C3Cl)C4=C(C(=CC=C4)C5=CN=C(C(=N5)OC)CNC[C@@H]6CCC(=O)N6)Cl
InChI
InChI=1S/C34H36Cl2N8O4/c1-47-33-27(15-37-13-19-9-11-29(45)41-19)39-17-25(43-33)23-7-3-5-21(31(23)35)22-6-4-8-24(32(22)36)26-18-40-28(34(44-26)48-2)16-38-14-20-10-12-30(46)42-20/h3-8,17-20,37-38H,9-16H2,1-2H3,(H,41,45)(H,42,46)/t19-,20-/m0/s1
InChIKey
OIIOPWHTJZYKIL-PMACEKPBSA-N
Computed Properties
Structural Parameters
Heavy atom count
48
Aromatic heavy atom count
24
Fraction Csp3
0.35
Rotatable bonds
13
H-bond acceptors
10
H-bond donors
4
Molar refractivity
182.8
TPSA
152.28
LogP / Solubility
WLOGP
4.33
MLOGP
3.87
XLogP3
2.2
Consensus LogP
3.47
Log S (ESOL)
-6.37
Class (ESOL)
Insoluble
Log S (Ali)
-8.36
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-9.31
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.87
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
6.5
Customers Also Viewed
-
2,2′-Bioxazole, 4,4′,5,5′-tetrahydro-4,4′-bis(1-methylpropyl)-, (4S,4’S)-
- CAS RN: 2374958-89-9
- Product Code: SSC-115387
-
Benzenemethanol, 2-[4-amino-6-[[(4-phenoxyphenyl)methyl]amino]-1,3,5-triazin-2-yl]-3-fluoro-
- CAS RN: 2375070-79-2
- Product Code: starshine_CAS2375070-79-2
- Purity/Analytical method: >99.0%
-
1-(tert-butyl) 3-methyl (S)-3-methylpyrrolidine-1,3-dicarboxylate
- CAS RN: 2375165-13-0
- Product Code: starshine_CAS2375165-13-0
-
-
-
1-Piperidinecarboxylic acid, 5-amino-2-methyl-, 1,1-dimethylethyl ester, (2S,5S)…
- CAS RN: 2375165-77-6
- Product Code: starshine_CAS2375165-77-6
- Purity/Analytical method: >99.0%
![CAS 2375070-79-2 Benzenemethanol, 2-[4-amino-6-[[(4-phenoxyphenyl)methyl]amino]-1,3,5-triazin-2-yl]-3-fluoro- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/2375070-79-2.gif)
