[email protected]
CAS 220127-57-1 Imatinib Mesylate molecular structure lightbox
CAS RN: 220127-57-1

Imatinib Mesylate

Product Availability

Choose a grade to view its available package options.

8 package records8 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20251022 1ml In stock Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250412 100g In stock Shanghai Inquiry
Batchno.20250620 100mg In stock Shanghai Inquiry
Batchno.20251209 10g In stock Shanghai, Shenzhen Inquiry
Batchno.20251114 1g In stock Shanghai, Shenzhen, Wuhan, Chengdu Inquiry
Batchno.20250416 250mg In stock Shanghai, Shenzhen, Tianjin Inquiry
Batchno.20250625 25g In stock Wuhan, Chengdu Inquiry
Batchno.20260129 5g In stock Shanghai, Tianjin Inquiry
  • Product code: SSC-105882
GET A QUOTE
Verified Factory Data

Supply Overview & Packaging Options

Packaging options, recorded purity, stock quantity and ship-from location below are generated from the current factory data table for this CAS.

  • Pack sizes on record: 1g, 5g, 10g, 25g, 100g
  • Available purity: ≥95%
  • Inventory rows with stock: 8
  • Bulk packaging: confirmed by inquiry
Request Bulk Quote

Available Pack Sizes & Stock

Specific stock quantities are shown below. Price is not displayed online and is confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 220127-57-1
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g -- 4 In Stock Beijing Inquiry
1g ≥95% 4 In Stock Hong Kong Inquiry
5g -- 2 In Stock Beijing Inquiry
5g ≥95% 2 In Stock Shenzhen Inquiry
10g -- 2 In Stock Shanghai Inquiry
10g ≥95% 2 In Stock Beijing Inquiry
25g -- 2 In Stock Shenzhen Inquiry
25g ≥95% 2 In Stock Beijing Inquiry
100g -- 0 Out of Stock Shanghai Inquiry
100g ≥95% 0 Out of Stock Shenzhen Inquiry

220127-57-1 / methanesulfonic acid;4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide

Standard CAS: 220127-57-1 Multi CAS: No
Basic Information Physical Properties Computed Properties

Basic Information

CAS
220127-57-1
Multi CAS
No
Molecular Formula
C30H35N7O4S
Molecular Weight
589.700000
Exact Mass
589.247124
SMILES
CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O
InChI
InChI=1S/C29H31N7O.CH4O3S/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36;1-5(2,3)4/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34);1H3,(H,2,3,4)
InChIKey
YLMAHDNUQAMNNX-UHFFFAOYSA-N

Physical Properties

Melting Point
MP: 226 °C (alpha form); 217 °C (beta form)
Appearance
White to off white to brownish or yellowish tinged crystalline powder
State
Solid

Computed Properties

Structural Parameters

Heavy atom count
42
Aromatic heavy atom count
24
Fraction Csp3
0.27
Rotatable bonds
7
H-bond acceptors
9
H-bond donors
3
Molar refractivity
164.37
TPSA
140.65

LogP / Solubility

WLOGP
4.09
MLOGP
3.65
XLogP3
4.09
Consensus LogP
3.94
Log S (ESOL)
-6.04
Class (ESOL)
Insoluble
Log S (Ali)
-7.35
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.73
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.41

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
No
Egan
No
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
5

Customers Also Viewed

Get In Touch

Contact Us