CAS RN: 2097132-94-8
BLU-667 (Pralsetinib)
Product Availability
Choose a grade to view its available package options.
12 package records12 with current stock3 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260315 | 10mg | In stock | Shandong, Hebei | Inquiry |
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20251130 | 100mg | In stock | Shanghai | Inquiry |
| Batchno.20251019 | 10mg | In stock | Shanghai | Inquiry |
| Batchno.20250324 | 1mg | In stock | Shanghai | Inquiry |
| Batchno.20251228 | 25mg | In stock | Shanghai | Inquiry |
| Batchno.20251129 | 50mg | In stock | Shanghai, Shenzhen | Inquiry |
| Batchno.20260413 | 5mg | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS2097132-94-8
- Purity/Analytical Methods: >99.0%
2097132-94-8 / N-[(1S)-1-[6-(4-fluoropyrazol-1-yl)-3-pyridinyl]ethyl]-1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]cyclohexane-1-carboxamide
Basic Information
CAS
2097132-94-8
Multi CAS
No
Molecular Formula
C27H32FN9O2
Molecular Weight
533.600000
Exact Mass
533.266299
SMILES
CC1=CC(=NN1)NC2=NC(=NC(=C2)C)C3CCC(CC3)(C(=O)N[C@@H](C)C4=CN=C(C=C4)N5C=C(C=N5)F)OC
InChI
InChI=1S/C27H32FN9O2/c1-16-11-22(33-23-12-17(2)35-36-23)34-25(31-16)19-7-9-27(39-4,10-8-19)26(38)32-18(3)20-5-6-24(29-13-20)37-15-21(28)14-30-37/h5-6,11-15,18-19H,7-10H2,1-4H3,(H,32,38)(H2,31,33,34,35,36)/t18-,19?,27?/m0/s1
InChIKey
GBLBJPZSROAGMF-SIYOEGHHSA-N
Computed Properties
Structural Parameters
Heavy atom count
39
Aromatic heavy atom count
22
Fraction Csp3
0.41
Rotatable bonds
8
H-bond acceptors
9
H-bond donors
3
Molar refractivity
142.2
TPSA
135.53
LogP / Solubility
WLOGP
4.2
MLOGP
3.74
XLogP3
3.1
Consensus LogP
3.68
Log S (ESOL)
-5.68
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.97
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.57
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.99
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
No
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
5.5
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