CAS RN: 2041075-86-7
AZD 5718)
Product Availability
Choose a grade to view its available package options.
5 package records4 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250410 | 100mg | In stock | Shanghai | Inquiry | |
| Batchno.20251109 | 10mg | In stock | Shanghai | Inquiry | |
| Batchno.20260130 | 10mg / 50mg | Out of stock | 8-10 business days | Inquiry | |
| Batchno.20260522 | 250mg | In stock | Shanghai | Inquiry | |
| Batchno.20251028 | 50mg | In stock | Shanghai | Inquiry |
- Product code: SSC-096032
Historical Factory Record
Historical Supply Reference
This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
- Pack sizes on record: 0.25g
- Available purity: ≥95%
- Inventory rows with stock: 0
- Bulk packaging: confirmed by inquiry
Reference Pack Sizes
Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.
| Pack Size | Recorded Purity | Available Qty | Ship From | Inquiry |
|---|---|---|---|---|
| 0.25g | ≥95% | 0 Out of Stock | Shanghai | Inquiry |
2041075-86-7 / trans-(1R,2R)-2-[4-(5-methyl-1H-pyrazol-3-yl)benzoyl]-N-(4-oxo-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-3-yl)cyclohexane-1-carboxamide
Basic Information
CAS
2041075-86-7
Multi CAS
No
Molecular Formula
C24H26N6O3
Molecular Weight
446.500000
Exact Mass
446.206639
SMILES
CC1=CC(=NN1)C2=CC=C(C=C2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NC4=C5C(=O)NCCN5N=C4
InChI
InChI=1S/C24H26N6O3/c1-14-12-19(29-28-14)15-6-8-16(9-7-15)22(31)17-4-2-3-5-18(17)23(32)27-20-13-26-30-11-10-25-24(33)21(20)30/h6-9,12-13,17-18H,2-5,10-11H2,1H3,(H,25,33)(H,27,32)(H,28,29)/t17-,18-/m1/s1
InChIKey
ROTWSDMXHVGAHZ-QZTJIDSGSA-N
Computed Properties
Structural Parameters
Heavy atom count
33
Aromatic heavy atom count
16
Fraction Csp3
0.38
Rotatable bonds
5
H-bond acceptors
6
H-bond donors
3
Molar refractivity
121.73
TPSA
121.77
LogP / Solubility
WLOGP
2.95
MLOGP
2.63
XLogP3
2.5
Consensus LogP
2.69
Log S (ESOL)
-4.5
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.35
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-5.61
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.35
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
4.5
Customers Also Viewed
-
BTR
- CAS RN: 2041283-06-9
- Product Code: starshine_CAS2041283-06-9
- Purity/Analytical method: >99.0%
-
tert-butyl (R)-3-(aminomethyl)-4,4-difluoropiperidine-1-carboxylate
- CAS RN: 2041786-50-7
- Product Code: starshine_CAS2041786-50-7
- Purity/Analytical method: >99.0%
-
[4,4′-Bis(1,1-dimethylethyl)-2,2′-bipyridine]bis[3,5-difluoro-2-(5-fluoro-2-pyridinyl)phenyl]iridium hexafluorophosphate, min. 98%
- CAS RN: 2042201-18-1
- Product Code: SSC-096064
-
“1,10-Phenanthroline, 2-(4-bromo-1-naphthalenyl)-9-phenyl-“
- CAS RN: 2042493-16-1
- Product Code: SSC-096073
-
Benzaldehyde, 4-[2,4-bis(4-formylphenyl)-1H-benzimidazol-7-yl]-
- CAS RN: 2042699-72-7
- Product Code: starshine_CAS2042699-72-7
- Purity/Analytical method: >99.0%
-
2-Pyrazinecarbonitrile, 6-ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-
- CAS RN: 2043019-99-2
- Product Code: starshine_CAS2043019-99-2
- Purity/Analytical method: >99.0%
![CAS 2042201-18-1 [4,4′-Bis(1,1-dimethylethyl)-2,2′-bipyridine]bis[3,5-difluoro-2-(5-fluoro-2-pyridinyl)phenyl]iridium hexafluorophosphate, min. 98% molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/2042201-18-1.gif)
![CAS 2042699-72-7 Benzaldehyde, 4-[2,4-bis(4-formylphenyl)-1H-benzimidazol-7-yl]- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/2042699-72-7.png)
![CAS 2043019-99-2 2-Pyrazinecarbonitrile, 6-ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/2043019-99-2.png)