[email protected]
CAS 18260-64-5 Pyrimidine, 4,6-difluoro-5-methyl- (8CI) molecular structure lightbox
CAS RN: 18260-64-5

Pyrimidine, 4,6-difluoro-5-methyl- (8CI)

Product Availability

Choose a grade to view its available package options.

1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20250712 100mg / 250mg / 1g Out of stock 5-7 business days Inquiry
  • Product code: starshine_CAS18260-64-5
  • Purity/Analytical Methods: >99.0%
GET A QUOTE

18260-64-5 / 4,6-difluoro-5-methylpyrimidine

Standard CAS: 18260-64-5 Multi CAS: No
Basic Information Computed Properties Safety & Transport

Basic Information

CAS
18260-64-5
Multi CAS
No
Molecular Formula
C5H4F2N2
Molecular Weight
130.100000
Exact Mass
130.034254
SMILES
CC1=C(N=CN=C1F)F
InChI
InChI=1S/C5H4F2N2/c1-3-4(6)8-2-9-5(3)7/h2H,1H3
InChIKey
FJIZSGSZCDMMMY-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
9
Aromatic heavy atom count
6
Fraction Csp3
0.2
H-bond acceptors
2
Molar refractivity
26.68
TPSA
25.78

LogP / Solubility

WLOGP
1.06
MLOGP
0.93
XLogP3
1.4
Consensus LogP
1.13
Log S (ESOL)
-1.81
Class (ESOL)
Soluble
Log S (Ali)
-1.39
Class (Ali)
Soluble
Log S (SILICOS-IT)
-1.39
Class (SILICOS-IT)
Soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.76

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5

Safety & Transport

Pictogram(s)
Flammable Corrosive Irritant
Signal
Danger
GHS Hazard Statements
H226 (100%): Flammable liquid and vapor [Warning Flammable liquids] H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes
P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501

Customers Also Viewed

Get In Touch

Contact Us