CAS RN: 18260-69-0
Pyrimidine, 4-amino-6-fluoro-5-methyl- (8CI)
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20250514 | 100mg / 250mg / 1g / 5g | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS18260-69-0
- Purity/Analytical Methods: >99.0%
18260-69-0 / 6-fluoro-5-methylpyrimidin-4-amine
Basic Information
CAS
18260-69-0
Multi CAS
No
Molecular Formula
C5H6FN3
Molecular Weight
127.120000
Exact Mass
127.054575
SMILES
CC1=C(N=CN=C1F)N
InChI
InChI=1S/C5H6FN3/c1-3-4(6)8-2-9-5(3)7/h2H,1H3,(H2,7,8,9)
InChIKey
PEXNNBPRBIMCKP-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
9
Aromatic heavy atom count
6
Fraction Csp3
0.2
H-bond acceptors
3
H-bond donors
1
Molar refractivity
31.14
TPSA
51.8
LogP / Solubility
WLOGP
0.51
MLOGP
0.44
XLogP3
0.7
Consensus LogP
0.55
Log S (ESOL)
-1.44
Class (ESOL)
Soluble
Log S (Ali)
-0.97
Class (Ali)
Very soluble
Log S (SILICOS-IT)
-0.91
Class (SILICOS-IT)
Very soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.14
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5
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