CAS RN: 1672666-82-8
HIF2α-IN-2
Product Availability
Choose a grade to view its available package options.
6 package records4 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20260614 | 100mg | In stock | Shanghai | Inquiry | |
| Batchno.20251029 | 10mg | In stock | Shanghai | Inquiry | |
| Batchno.20251210 | 25mg | In stock | Shanghai | Inquiry | |
| Batchno.20260401 | 50mg | In stock | Shanghai | Inquiry | |
| Batchno.20260622 | 5mg | Out of stock | 5-7 business days | Inquiry | |
| Batchno.20250415 | 5mg | Out of stock | Inquiry |
- Product code: starshine_CAS1672666-82-8
- Purity/Analytical Methods: >99.0%
1672666-82-8 / 3-fluoro-5-[(2-fluoro-1-hydroxy-7-methylsulfonyl-2,3-dihydro-1H-inden-4-yl)oxy]benzonitrile
Basic Information
CAS
1672666-82-8
Multi CAS
No
Molecular Formula
C17H13F2NO4S
Molecular Weight
365.400000
Exact Mass
365.053335
SMILES
CS(=O)(=O)C1=C2C(C(CC2=C(C=C1)OC3=CC(=CC(=C3)C#N)F)F)O
InChI
InChI=1S/C17H13F2NO4S/c1-25(22,23)15-3-2-14(12-7-13(19)17(21)16(12)15)24-11-5-9(8-20)4-10(18)6-11/h2-6,13,17,21H,7H2,1H3
InChIKey
GTHLUQQEKIJSME-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
25
Aromatic heavy atom count
12
Fraction Csp3
0.24
Rotatable bonds
3
H-bond acceptors
5
H-bond donors
1
Molar refractivity
84.3
TPSA
87.39
LogP / Solubility
WLOGP
2.82
MLOGP
2.5
XLogP3
2.1
Consensus LogP
2.47
Log S (ESOL)
-4.04
Class (ESOL)
Slightly soluble
Log S (Ali)
-4.59
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.74
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.95
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5
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