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CAS 1627856-64-7 RET Kinase inhibitor 1 molecular structure lightbox
CAS RN: 1627856-64-7

RET Kinase inhibitor 1

Product Availability

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12 package records11 with current stock3 grade groups
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20260627 10mg In stock Inquiry
Batchno.20250518 25mg In stock Inquiry
Batchno.20250816 50mg In stock Inquiry
Batchno.20250514 5mg Out of stock Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250127 1mg / 5mg / 25mg Confirm by inquiry Shanghai 5-7 business days Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250130 100mg In stock Shanghai Inquiry
Batchno.20251006 10mg In stock Shanghai Inquiry
Batchno.20260127 1mg In stock Shanghai Inquiry
Batchno.20260410 250mg In stock Shanghai Inquiry
Batchno.20250411 25mg In stock Shanghai Inquiry
Batchno.20260629 50mg In stock Shanghai Inquiry
Batchno.20250118 5mg In stock Shanghai Inquiry
  • Product code: SSC-070164
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.25g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1627856-64-7
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.25g ≥95% 0 Out of Stock Beijing Inquiry

1627856-64-7 / 2-[4-(4-ethoxy-6-oxo-1H-pyridin-3-yl)-2-fluorophenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide

Standard CAS: 1627856-64-7 Multi CAS: No
Basic Information Computed Properties Safety & Transport

Basic Information

CAS
1627856-64-7
Multi CAS
No
Molecular Formula
C22H21F4N3O4
Molecular Weight
467.400000
Exact Mass
467.146819
SMILES
CCOC1=CC(=O)NC=C1C2=CC(=C(C=C2)CC(=O)NC3=NOC(=C3)C(C)(C)C(F)(F)F)F
InChI
InChI=1S/C22H21F4N3O4/c1-4-32-16-9-19(30)27-11-14(16)12-5-6-13(15(23)7-12)8-20(31)28-18-10-17(33-29-18)21(2,3)22(24,25)26/h5-7,9-11H,4,8H2,1-3H3,(H,27,30)(H,28,29,31)
InChIKey
IDXKJSSOUXWLDB-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
33
Aromatic heavy atom count
17
Fraction Csp3
0.32
Rotatable bonds
7
H-bond acceptors
5
H-bond donors
2
Molar refractivity
111.54
TPSA
97.22

LogP / Solubility

WLOGP
4.59
MLOGP
4.07
XLogP3
3.4
Consensus LogP
4.02
Log S (ESOL)
-5.55
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.71
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.35
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.31

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
2.5

Safety & Transport

Pictogram(s)
Health Hazard
Signal
Warning
GHS Hazard Statements
H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
Precautionary Statement Codes
P203, P280, P318, P405, and P501

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