CAS RN: 149709-44-4
Sacubitril Impurity 7
Product Availability
Choose a grade to view its available package options.
9 package records8 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250501 | 100mg | In stock | Shanghai, Tianjin | Inquiry |
| Batchno.20250814 | 10mg | In stock | Shanghai | Inquiry |
| Batchno.20251001 | 1g | Out of stock | Inquiry | |
| Batchno.20260425 | 1mg | In stock | Shanghai, Tianjin, Wuhan | Inquiry |
| Batchno.20250829 | 250mg | In stock | Shanghai | Inquiry |
| Batchno.20250408 | 25mg | In stock | Shanghai, Tianjin | Inquiry |
| Batchno.20260320 | 50mg | In stock | Shanghai | Inquiry |
| Batchno.20250203 | 5mg | In stock | Shanghai | Inquiry |
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260308 | 2mg / 5mg / 10mg / 100mg | Confirm by inquiry | Shanghai | Inquiry |
- Product code: starshine_CAS149709-44-4
- Purity/Analytical Methods: >99.0%
149709-44-4 / (2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid
Basic Information
CAS
149709-44-4
Multi CAS
No
Molecular Formula
C22H25NO5
Molecular Weight
383.400000
Exact Mass
383.173273
SMILES
C[C@H](C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O)C(=O)O
InChI
InChI=1S/C22H25NO5/c1-15(22(27)28)13-19(23-20(24)11-12-21(25)26)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h2-10,15,19H,11-14H2,1H3,(H,23,24)(H,25,26)(H,27,28)/t15-,19+/m1/s1
InChIKey
DOBNVUFHFMVMDB-BEFAXECRSA-N
Computed Properties
Structural Parameters
Heavy atom count
28
Aromatic heavy atom count
12
Fraction Csp3
0.32
Rotatable bonds
10
H-bond acceptors
3
H-bond donors
3
Molar refractivity
105.8
TPSA
103.7
LogP / Solubility
WLOGP
3.36
MLOGP
2.98
XLogP3
3
Consensus LogP
3.11
Log S (ESOL)
-3.99
Class (ESOL)
Poorly soluble
Log S (Ali)
-5.13
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-6.14
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.68
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5
Safety & Transport
Pictogram(s)
Irritant
Health Hazard
Signal
Danger
GHS Hazard Statements
H336 (100%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]
H372 (100%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]
Precautionary Statement Codes
P260, P261, P264, P270, P271, P304+P340, P319, P403+P233, P405, and P501
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![CAS 149709-59-1 (R,E)-ethyl 5-([1,1′-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/149709-59-1.gif)
