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CAS 147201-04-5 5′-O-(4,4-Dimethoxytrityl)-2′-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3′-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite molecular structure lightbox
CAS RN: 147201-04-5

5′-O-(4,4-Dimethoxytrityl)-2′-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3′-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

Product Availability

Choose a grade to view its available package options.

7 package records7 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250828 100mg In stock Shanghai, Tianjin, Wuhan Inquiry
Batchno.20251227 10g In stock Shanghai Inquiry
Batchno.20251008 1g In stock Shanghai, Shenzhen Inquiry
Batchno.20250909 250mg In stock Shanghai, Tianjin, Wuhan Inquiry
Batchno.20250620 25g In stock Shanghai Inquiry
Batchno.20251009 5g In stock Shanghai, Shenzhen Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250918 250mg / 1g / 5g Confirm by inquiry Shanghai, Shandong Inquiry
  • Product code: SSC-057989
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Verified Factory Data

Supply Overview & Packaging Options

Packaging options, recorded purity, stock quantity and ship-from location below are generated from the current factory data table for this CAS.

  • Pack sizes on record: 10g, 0.25g, 1g, 5g, 25g, 100g
  • Available purity: >98%
  • Inventory rows with stock: 6
  • Bulk packaging: confirmed by inquiry
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Available Pack Sizes & Stock

Specific stock quantities are shown below. Price is not displayed online and is confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 147201-04-5
Pack Size Recorded Purity Available Qty Ship From Inquiry
10g >98% 2 In Stock Shanghai Inquiry
0.25g >98% 1 In Stock Beijing Inquiry
1g >98% 1 In Stock Shenzhen Inquiry
5g >98% 1 In Stock Shanghai Inquiry
25g >98% 1 In Stock Hong Kong Inquiry
100g >98% 1 In Stock Shenzhen Inquiry

147201-04-5 / N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

Standard CAS: 147201-04-5 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
147201-04-5
Multi CAS
No
Molecular Formula
C50H68N7O9PSi
Molecular Weight
970.200000
Exact Mass
969.458540
SMILES
CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)O[Si](C)(C)C(C)(C)C
InChI
InChI=1S/C50H68N7O9PSi/c1-32(2)45(58)54-48-53-44-41(46(59)55-48)52-31-56(44)47-43(66-68(12,13)49(7,8)9)42(65-67(63-29-17-28-51)57(33(3)4)34(5)6)40(64-47)30-62-50(35-18-15-14-16-19-35,36-20-24-38(60-10)25-21-36)37-22-26-39(61-11)27-23-37/h14-16,18-27,31-34,40,42-43,47H,17,29-30H2,1-13H3,(H2,53,54,55,58,59)/t40-,42-,43-,47-,67?/m1/s1
InChIKey
PGJKESPHANLWME-FTZVBZPOSA-N

Computed Properties

Structural Parameters

Heavy atom count
68
Aromatic heavy atom count
27
Fraction Csp3
0.5
Rotatable bonds
21
H-bond acceptors
14
H-bond donors
2
Molar refractivity
265.95
TPSA
184.31

LogP / Solubility

WLOGP
9.69
MLOGP
8.62
XLogP3
9.69
Consensus LogP
9.33
Log S (ESOL)
-10.87
Class (ESOL)
Insoluble
Log S (Ali)
-14.51
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-16.53
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.76

Drug-likeness / Medicinal Chemistry

Lipinski
No
Ghose
No
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.17
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
8

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