[email protected]
CAS 143946-48-9 4-CHLORO-5-METHYLQUINOLINE molecular structure lightbox
CAS RN: 143946-48-9

4-CHLORO-5-METHYLQUINOLINE

Product Availability

Choose a grade to view its available package options.

1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20250220 50mg / 250mg Out of stock 8-10 business days Inquiry
  • Product code: starshine_CAS143946-48-9
  • Purity/Analytical Methods: >99.0%
GET A QUOTE

143946-48-9 / 4-chloro-5-methylquinoline

Standard CAS: 143946-48-9 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
143946-48-9
Multi CAS
No
Molecular Formula
C10H8ClN
Molecular Weight
177.630000
Exact Mass
177.034527
SMILES
CC1=C2C(=CC=C1)N=CC=C2Cl
InChI
InChI=1S/C10H8ClN/c1-7-3-2-4-9-10(7)8(11)5-6-12-9/h2-6H,1H3
InChIKey
UCSWAUFCOHKRMT-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
12
Aromatic heavy atom count
10
Fraction Csp3
0.1
H-bond acceptors
1
Molar refractivity
51.49
TPSA
12.89

LogP / Solubility

WLOGP
3.2
MLOGP
2.81
XLogP3
3.2
Consensus LogP
3.07
Log S (ESOL)
-3.57
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.32
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.47
Class (SILICOS-IT)
Poorly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-1.53

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5

Customers Also Viewed

Get In Touch

Contact Us