![CAS 142873-41-4 5-Benzofuranamine, 2,3-dihydro-2,4,6,7-tetramethyl-2-[(4-phenyl-1-piperidinyl)methyl]- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/142873-41-4.gif)
CAS RN: 142873-41-4
5-Benzofuranamine, 2,3-dihydro-2,4,6,7-tetramethyl-2-[(4-phenyl-1-piperidinyl)methyl]-
Product Availability
Available package options are listed below.
1 package records0 with current stock
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20260111 | 1mg | Out of stock | 30 business days | Inquiry |
- Product code: starshine_CAS142873-41-4
- Purity/Analytical Methods: >99.0%
142873-41-4 / 2,4,6,7-tetramethyl-2-[(4-phenylpiperidin-1-yl)methyl]-3H-1-benzofuran-5-amine
Basic Information
CAS
142873-41-4
Multi CAS
No
Molecular Formula
C24H32N2O
Molecular Weight
364.500000
Exact Mass
364.251464
SMILES
CC1=C(C2=C(CC(O2)(C)CN3CCC(CC3)C4=CC=CC=C4)C(=C1N)C)C
InChI
InChI=1S/C24H32N2O/c1-16-17(2)23-21(18(3)22(16)25)14-24(4,27-23)15-26-12-10-20(11-13-26)19-8-6-5-7-9-19/h5-9,20H,10-15,25H2,1-4H3
InChIKey
OFJJFTDZPRQPBY-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
27
Aromatic heavy atom count
12
Fraction Csp3
0.5
Rotatable bonds
3
H-bond acceptors
3
H-bond donors
1
Molar refractivity
112.66
TPSA
38.49
LogP / Solubility
WLOGP
4.77
MLOGP
4.21
XLogP3
4.9
Consensus LogP
4.63
Log S (ESOL)
-5.23
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.99
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-6.35
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.56
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
3.5
Customers Also Viewed
-
2,2,4,6,7-Pentamethyldihydrobenzofuran
- CAS RN: 142874-81-5
- Product Code: starshine_CAS142874-81-5
- Purity/Analytical method: >99.0%
-
U-73343
- CAS RN: 142878-12-4
- Product Code: starshine_CAS142878-12-4
- Purity/Analytical method: >99.0%
-
4-bromo-p-quaterphenyl
- CAS RN: 142878-37-3
- Product Code: starshine_CAS142878-37-3
- Purity/Analytical method: >99.0%
-
-
-
6 ETHOXY-1-INDANONE
- CAS RN: 142888-69-5
- Product Code: starshine_CAS142888-69-5
- Purity/Analytical method: >99.0%
