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CAS RN: 1428729-56-9
KIN1148
Product Availability
Choose a grade to view its available package options.
13 package records12 with current stock3 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250430 | 1mg / 5mg / 25mg / 100mg | Confirm by inquiry | Shanghai, Shandong | Inquiry |
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250114 | 100mg | In stock | Shanghai | Inquiry |
| Batchno.20260406 | 10mg | In stock | Shanghai, Wuhan | Inquiry |
| Batchno.20250805 | 1mg | In stock | Shanghai | Inquiry |
| Batchno.20260223 | 250mg | In stock | Shanghai | Inquiry |
| Batchno.20250909 | 50mg | In stock | Shanghai | Inquiry |
| Batchno.20250612 | 5mg | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS1428729-56-9
- Purity/Analytical Methods: >99.0%
1428729-56-9 / N-([1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)naphthalene-2-carboxamide
Basic Information
CAS
1428729-56-9
Multi CAS
No
Molecular Formula
C19H11N3OS2
Molecular Weight
361.400000
Exact Mass
361.034354
SMILES
C1=CC=C2C=C(C=CC2=C1)C(=O)NC3=NC4=C(S3)C5=C(C=C4)SC=N5
InChI
InChI=1S/C19H11N3OS2/c23-18(13-6-5-11-3-1-2-4-12(11)9-13)22-19-21-14-7-8-15-16(17(14)25-19)20-10-24-15/h1-10H,(H,21,22,23)
InChIKey
YAISOECYKYATLL-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
25
Aromatic heavy atom count
22
Rotatable bonds
2
H-bond acceptors
5
H-bond donors
1
Molar refractivity
104.7
TPSA
54.88
LogP / Solubility
WLOGP
5.31
MLOGP
4.69
XLogP3
5.3
Consensus LogP
5.1
Log S (ESOL)
-5.95
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.36
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-6.66
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.15
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5
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![CAS 1428774-45-1 1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1428774-45-1.gif)
