CAS RN: 1421365-63-0
5-Chloro-2-(9H-fluoren-9-yl)-4-(4-methoxyphenoxy)-3(2H)-pyridazinone
Product Availability
Choose a grade to view its available package options.
7 package records7 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20251018 | 100mg | In stock | Shanghai | Inquiry |
| Batchno.20251031 | 10mg | In stock | Shanghai | Inquiry |
| Batchno.20251230 | 1mg | In stock | Shanghai | Inquiry |
| Batchno.20250316 | 250mg | In stock | Shanghai | Inquiry |
| Batchno.20250819 | 25mg | In stock | Shanghai | Inquiry |
| Batchno.20250713 | 50mg | In stock | Shanghai | Inquiry |
| Batchno.20260512 | 5mg | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS1421365-63-0
- Purity/Analytical Methods: >99.0%
1421365-63-0 / 5-chloro-2-(9H-fluoren-9-yl)-4-(4-methoxyphenoxy)pyridazin-3-one
Basic Information
CAS
1421365-63-0
Multi CAS
No
Molecular Formula
C24H17ClN2O3
Molecular Weight
416.900000
Exact Mass
416.092770
SMILES
COC1=CC=C(C=C1)OC2=C(C=NN(C2=O)C3C4=CC=CC=C4C5=CC=CC=C35)Cl
InChI
InChI=1S/C24H17ClN2O3/c1-29-15-10-12-16(13-11-15)30-23-21(25)14-26-27(24(23)28)22-19-8-4-2-6-17(19)18-7-3-5-9-20(18)22/h2-14,22H,1H3
InChIKey
QHVSQUYCVUHYKT-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
30
Aromatic heavy atom count
24
Fraction Csp3
0.08
Rotatable bonds
4
H-bond acceptors
5
Molar refractivity
115.69
TPSA
53.35
LogP / Solubility
WLOGP
5.32
MLOGP
4.7
XLogP3
4.9
Consensus LogP
4.97
Log S (ESOL)
-6.1
Class (ESOL)
Insoluble
Log S (Ali)
-6.82
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.26
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.49
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5
Safety & Transport
Pictogram(s)
Irritant
Signal
Warning
GHS Hazard Statements
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
H413 (100%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]
Precautionary Statement Codes
P264, P270, P273, P301+P317, P330, and P501
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