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CAS 1392275-56-7 Tenofovir alafenamide hemifumarate molecular structure lightbox
CAS RN: 1392275-56-7

Tenofovir alafenamide hemifumarate

Product Availability

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5 package records5 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260327 100mg In stock Shanghai Inquiry
Batchno.20260621 1g In stock Shanghai, Shenzhen, Wuhan Inquiry
Batchno.20250823 250mg In stock Shanghai, Shenzhen, Tianjin, Wuhan, Chengdu Inquiry
Batchno.20250106 25g In stock Shenzhen, Tianjin, Wuhan Inquiry
Batchno.20250322 5g In stock Shenzhen, Tianjin, Wuhan, Chengdu Inquiry
  • Product code: SSC-049652
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 1g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1392275-56-7
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g ≥95% 0 Out of Stock Hong Kong Inquiry

1392275-56-7 / (E)-but-2-enedioic acid;bis(propan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate)

Standard CAS: 1392275-56-7 Multi CAS: No
Basic Information Computed Properties Safety & Transport

Basic Information

CAS
1392275-56-7
Multi CAS
No
Molecular Formula
C46H62N12O14P2
Molecular Weight
1069.000000
Exact Mass
1068.398369
SMILES
C[C@H](CN1C=NC2=C(N=CN=C21)N)OC[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC3=CC=CC=C3.C[C@H](CN1C=NC2=C(N=CN=C21)N)OC[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC3=CC=CC=C3.C(=C/C(=O)O)\C(=O)O
InChI
InChI=1S/2C21H29N6O5P.C4H4O4/c2*1-14(2)31-21(28)16(4)26-33(29,32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27;5-3(6)1-2-4(7)8/h2*5-9,11-12,14-16H,10,13H2,1-4H3,(H,26,29)(H2,22,23,24);1-2H,(H,5,6)(H,7,8)/b;;2-1+/t2*15-,16+,33+;/m11./s1
InChIKey
SVUJNSGGPUCLQZ-FQQAACOVSA-N

Computed Properties

Structural Parameters

Heavy atom count
74
Aromatic heavy atom count
30
Fraction Csp3
0.39
Rotatable bonds
24
H-bond acceptors
22
H-bond donors
6
Molar refractivity
271.71
TPSA
361.56

LogP / Solubility

WLOGP
5.66
MLOGP
5.08
XLogP3
5.66
Consensus LogP
5.47
Log S (ESOL)
-8.75
Class (ESOL)
Insoluble
Log S (Ali)
-12.41
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-14.18
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-5.22

Drug-likeness / Medicinal Chemistry

Lipinski
No
Ghose
No
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.17
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
8.5

Safety & Transport

Pictogram(s)
Irritant Health Hazard
Signal
Warning
GHS Hazard Statements
H302 (25%): Harmful if swallowed [Warning Acute toxicity, oral] H373 (75%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
Precautionary Statement Codes
P260, P264, P270, P301+P317, P319, P330, and P501

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