CAS RN: 1386874-06-1
LY3023414
Product Availability
Choose a grade to view its available package options.
7 package records6 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20251216 | 100mg | In stock | Shanghai | Inquiry | |
| Batchno.20260419 | 10mg | In stock | Shanghai | Inquiry | |
| Batchno.20250824 | 1mg | In stock | Shanghai | Inquiry | |
| Batchno.20250123 | 250mg | In stock | Shanghai | Inquiry | |
| Batchno.20251102 | 25mg | In stock | Shanghai | Inquiry | |
| Batchno.20251221 | 50mg | In stock | Shanghai | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20251031 | 5mg / 25mg / 100mg | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS1386874-06-1
- Purity/Analytical Methods: >99.0%
1386874-06-1 / 8-[5-(2-hydroxypropan-2-yl)-3-pyridinyl]-1-[(2S)-2-methoxypropyl]-3-methylimidazo[4,5-c]quinolin-2-one
Basic Information
CAS
1386874-06-1
Multi CAS
No
Molecular Formula
C23H26N4O3
Molecular Weight
406.500000
Exact Mass
406.200491
SMILES
C[C@@H](CN1C2=C3C=C(C=CC3=NC=C2N(C1=O)C)C4=CC(=CN=C4)C(C)(C)O)OC
InChI
InChI=1S/C23H26N4O3/c1-14(30-5)13-27-21-18-9-15(16-8-17(11-24-10-16)23(2,3)29)6-7-19(18)25-12-20(21)26(4)22(27)28/h6-12,14,29H,13H2,1-5H3/t14-/m0/s1
InChIKey
ACCFLVVUVBJNGT-AWEZNQCLSA-N
Computed Properties
Structural Parameters
Heavy atom count
30
Aromatic heavy atom count
19
Fraction Csp3
0.35
Rotatable bonds
5
H-bond acceptors
7
H-bond donors
1
Molar refractivity
117.43
TPSA
82.17
LogP / Solubility
WLOGP
3.21
MLOGP
2.85
XLogP3
1.7
Consensus LogP
2.59
Log S (ESOL)
-4.52
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.21
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-5.57
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.92
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5
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