[email protected]
CAS 1384424-80-9 1-(7-Methoxyquinolin-4-yl)-3-[6-(trifluoromethyl)pyridin-2-yl]urea molecular structure lightbox
CAS RN: 1384424-80-9

1-(7-Methoxyquinolin-4-yl)-3-[6-(trifluoromethyl)pyridin-2-yl]urea

Product Availability

Choose a grade to view its available package options.

10 package records8 with current stock3 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250214 10mg In stock Inquiry
Batchno.20250901 250mg Out of stock Inquiry
Batchno.20250903 50mg In stock Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260623 10mg / 50mg / 250mg Confirm by inquiry Shanghai Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250928 100mg In stock Shanghai Inquiry
Batchno.20250925 10mg In stock Shanghai Inquiry
Batchno.20260625 250mg Out of stock Inquiry
Batchno.20260521 25mg In stock Shanghai Inquiry
Batchno.20250302 50mg In stock Shanghai Inquiry
Batchno.20260122 5mg In stock Shanghai Inquiry
  • Product code: starshine_CAS1384424-80-9
  • Purity/Analytical Methods: >99.0%
GET A QUOTE

1384424-80-9 / 1-(7-methoxyquinolin-4-yl)-3-[6-(trifluoromethyl)-2-pyridinyl]urea

Standard CAS: 1384424-80-9 Multi CAS: No
Basic Information Computed Properties Safety & Transport

Basic Information

CAS
1384424-80-9
Multi CAS
No
Molecular Formula
C17H13F3N4O2
Molecular Weight
362.310000
Exact Mass
362.099060
SMILES
COC1=CC2=NC=CC(=C2C=C1)NC(=O)NC3=CC=CC(=N3)C(F)(F)F
InChI
InChI=1S/C17H13F3N4O2/c1-26-10-5-6-11-12(7-8-21-13(11)9-10)22-16(25)24-15-4-2-3-14(23-15)17(18,19)20/h2-9H,1H3,(H2,21,22,23,24,25)
InChIKey
VQPBIJGXSXEOCU-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
26
Aromatic heavy atom count
16
Fraction Csp3
0.12
Rotatable bonds
3
H-bond acceptors
4
H-bond donors
2
Molar refractivity
90.18
TPSA
76.14

LogP / Solubility

WLOGP
4.3
MLOGP
3.8
XLogP3
2.9
Consensus LogP
3.67
Log S (ESOL)
-5.05
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.64
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-5.95
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.88

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
2.5

Safety & Transport

Pictogram(s)
Acute Toxic Irritant
Signal
Danger
GHS Hazard Statements
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral] H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes
P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Customers Also Viewed

Get In Touch

Contact Us