CAS RN: 1382979-44-3
GDC-0084
Product Availability
Choose a grade to view its available package options.
8 package records7 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250728 | 100mg | In stock | Shanghai | Inquiry |
| Batchno.20251125 | 10mg | In stock | Shanghai | Inquiry |
| Batchno.20260127 | 1g | Out of stock | Inquiry | |
| Batchno.20251102 | 1mg | In stock | Shanghai | Inquiry |
| Batchno.20260505 | 250mg | In stock | Shanghai | Inquiry |
| Batchno.20250709 | 25mg | In stock | Shanghai | Inquiry |
| Batchno.20250515 | 50mg | In stock | Shanghai | Inquiry |
| Batchno.20260104 | 5mg | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS1382979-44-3
- Purity/Analytical Methods: >99.0%
1382979-44-3 / 5-(6,6-dimethyl-4-morpholin-4-yl-8,9-dihydropurino[8,9-c][1,4]oxazin-2-yl)pyrimidin-2-amine
Basic Information
CAS
1382979-44-3
Multi CAS
No
Molecular Formula
C18H22N8O2
Molecular Weight
382.400000
Exact Mass
382.186572
SMILES
CC1(C2=NC3=C(N2CCO1)N=C(N=C3N4CCOCC4)C5=CN=C(N=C5)N)C
InChI
InChI=1S/C18H22N8O2/c1-18(2)16-22-12-14(25-3-6-27-7-4-25)23-13(11-9-20-17(19)21-10-11)24-15(12)26(16)5-8-28-18/h9-10H,3-8H2,1-2H3,(H2,19,20,21)
InChIKey
LGWACEZVCMBSKW-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
28
Aromatic heavy atom count
15
Fraction Csp3
0.5
Rotatable bonds
2
H-bond acceptors
10
H-bond donors
1
Molar refractivity
102.77
TPSA
117.1
LogP / Solubility
WLOGP
0.97
MLOGP
0.87
XLogP3
-0.3
Consensus LogP
0.51
Log S (ESOL)
-3.08
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.39
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.19
Class (SILICOS-IT)
Poorly soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-4.37
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5
Customers Also Viewed
-
![CAS 1383056-73-2 2-(tert-butoxycarbonylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid molecular structure](data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%200%200'%3E%3C/svg%3E)
2-(tert-butoxycarbonylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
- CAS RN: 1383056-73-2
- Product Code: SSC-048216
-
-
tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate
- CAS RN: 1383133-23-0
- Product Code: SSC-048228
-
(R)-4-(2,4-diMethoxybenzyl)-3-Methylpiperazin-2-one
- CAS RN: 1383146-20-0
- Product Code: SSC-048229
-
N-Pyridin-2-yl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide
- CAS RN: 1383385-64-5
- Product Code: SSC-048240
-
3,3′,3”-[(1,3,5-triazine-2,4,6-triyl)tris(azanediyl)]tribenzoic acid
- CAS RN: 1383425-68-0
- Product Code: SSC-048241
![CAS 1383056-73-2 2-(tert-butoxycarbonylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1383056-73-2.gif)
![CAS 1383133-23-0 tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/CB23308820(1).gif)
.gif)
![CAS 1383385-64-5 N-Pyridin-2-yl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1383385-64-5.gif)
![CAS 1383425-68-0 3,3′,3”-[(1,3,5-triazine-2,4,6-triyl)tris(azanediyl)]tribenzoic acid molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1383425-68-0.gif)