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CAS 1380300-25-3 2-(Cyclopropylmethyl)-2,8-diazaspiro[4.5]decan-3-one hydrochloride molecular structure lightbox
CAS RN: 1380300-25-3

2-(Cyclopropylmethyl)-2,8-diazaspiro[4.5]decan-3-one hydrochloride

Product Availability

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1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20260207 250mg Out of stock 15 business days Inquiry
  • Product code: starshine_CAS1380300-25-3
  • Purity/Analytical Methods: >99.0%
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1380300-25-3 / 2-(cyclopropylmethyl)-2,8-diazaspiro[4.5]decan-3-one;hydrochloride

Standard CAS: 1380300-25-3 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
1380300-25-3
Multi CAS
No
Molecular Formula
C12H21ClN2O
Molecular Weight
244.760000
Exact Mass
244.134241
SMILES
C1CC1CN2CC3(CCNCC3)CC2=O.Cl
InChI
InChI=1S/C12H20N2O.ClH/c15-11-7-12(3-5-13-6-4-12)9-14(11)8-10-1-2-10;/h10,13H,1-9H2;1H
InChIKey
QLLACYZHJJVIGV-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
16
Fraction Csp3
0.92
Rotatable bonds
2
H-bond acceptors
2
H-bond donors
1
Molar refractivity
65.71
TPSA
32.34

LogP / Solubility

WLOGP
1.42
MLOGP
1.26
XLogP3
1.42
Consensus LogP
1.37
Log S (ESOL)
-2.12
Class (ESOL)
Moderately soluble
Log S (Ali)
-2.59
Class (Ali)
Moderately soluble
Log S (SILICOS-IT)
-2.67
Class (SILICOS-IT)
Moderately soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.2

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
2.5

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