![CAS 1353947-01-9 Diethyl-[6-(3-MethylaMino-piperidin-1-yl)-pyriMidin-4-yl]-aMine hydrochloride molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/CB82581198(1).gif)
CAS RN: 1353947-01-9
Diethyl-[6-(3-MethylaMino-piperidin-1-yl)-pyriMidin-4-yl]-aMine hydrochloride
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20260324 | 100mg / 250mg | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS1353947-01-9
- Purity/Analytical Methods: >99.0%
1353947-01-9 / N,N-diethyl-6-[3-(methylamino)piperidin-1-yl]pyrimidin-4-amine;hydrochloride
Basic Information
CAS
1353947-01-9
Multi CAS
No
Molecular Formula
C14H26ClN5
Molecular Weight
299.840000
Exact Mass
299.187674
SMILES
CCN(CC)C1=NC=NC(=C1)N2CCCC(C2)NC.Cl
InChI
InChI=1S/C14H25N5.ClH/c1-4-18(5-2)13-9-14(17-11-16-13)19-8-6-7-12(10-19)15-3;/h9,11-12,15H,4-8,10H2,1-3H3;1H
InChIKey
GXPOPHZGURZPPY-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
20
Aromatic heavy atom count
6
Fraction Csp3
0.71
Rotatable bonds
5
H-bond acceptors
5
H-bond donors
1
Molar refractivity
87.14
TPSA
44.29
LogP / Solubility
WLOGP
1.93
MLOGP
1.71
XLogP3
1.93
Consensus LogP
1.86
Log S (ESOL)
-2.81
Class (ESOL)
Moderately soluble
Log S (Ali)
-3.41
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.81
Class (SILICOS-IT)
Poorly soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.18
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
Yes
Synthetic Accessibility
2
Customers Also Viewed
-
2,4-Dichloro-N-Methyl-N-piperidin-3-yl-benzenesulfonaMide hydrochloride
- CAS RN: 1353947-18-8
- Product Code: starshine_CAS1353947-18-8
- Purity/Analytical method: >99.0%
-
2,3-Dihydro-benzo[1,4]dioxine-6-carboxylic acid piperidin-3-ylaMide hydrochloride
- CAS RN: 1353948-20-5
- Product Code: SSC-043662
-
2-(3-Methyl-piperazin-1-yl)-benzooxazole hydrochloride
- CAS RN: 1353948-40-9
- Product Code: SSC-043663
-
2-Methyl-1-(toluene-3-sulfonyl)-piperazine hydrochloride
- CAS RN: 1353951-47-9
- Product Code: starshine_CAS1353951-47-9
- Purity/Analytical method: >99.0%
-
Benzo[1,3]dioxole-5-carboxylic acid piperidin-3-ylaMide hydrochloride
- CAS RN: 1353951-66-2
- Product Code: starshine_CAS1353951-66-2
- Purity/Analytical method: >99.0%
-
2-Chloro-N-piperidin-4-yl-isonicotinaMide hydrochloride
- CAS RN: 1353951-89-9
- Product Code: starshine_CAS1353951-89-9
- Purity/Analytical method: >99.0%
.gif)
![CAS 1353948-20-5 2,3-Dihydro-benzo[1,4]dioxine-6-carboxylic acid piperidin-3-ylaMide hydrochloride molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/CB72578627(1).gif)
.gif)
.gif)
![CAS 1353951-66-2 Benzo[1,3]dioxole-5-carboxylic acid piperidin-3-ylaMide hydrochloride molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/CB82581002(1).gif)
.gif)