![CAS 1353637-44-1 6-chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[4,3-c]pyridine molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1353637-44-1.gif)
CAS RN: 1353637-44-1
6-chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[4,3-c]pyridine
- Product code: SSC-043583
Historical Factory Record
Historical Supply Reference
This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
- Pack sizes on record: 1g
- Available purity: ＞97%
- Inventory rows with stock: 0
- Bulk packaging: confirmed by inquiry
Reference Pack Sizes
Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.
| Pack Size | Recorded Purity | Available Qty | Ship From | Inquiry |
|---|---|---|---|---|
| 1g | ＞97% | 0 Out of Stock | Hong Kong | Inquiry |
1353637-44-1 / 6-chloro-1-(oxan-2-yl)pyrazolo[4,3-c]pyridine
Basic Information
CAS
1353637-44-1
Multi CAS
No
Molecular Formula
C11H12ClN3O
Molecular Weight
237.680000
Exact Mass
237.066890
SMILES
C1CCOC(C1)N2C3=CC(=NC=C3C=N2)Cl
InChI
InChI=1S/C11H12ClN3O/c12-10-5-9-8(6-13-10)7-14-15(9)11-3-1-2-4-16-11/h5-7,11H,1-4H2
InChIKey
OUIMHYFRCMWCEA-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
16
Aromatic heavy atom count
9
Fraction Csp3
0.45
Rotatable bonds
1
H-bond acceptors
4
Molar refractivity
61.38
TPSA
39.94
LogP / Solubility
WLOGP
2.78
MLOGP
2.45
XLogP3
2.2
Consensus LogP
2.48
Log S (ESOL)
-3.42
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.52
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.64
Class (SILICOS-IT)
Poorly soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.19
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
2
Customers Also Viewed
-
![CAS 1353644-70-8 (3aR,6aR)-N-(4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)-1-methylhexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxamide molecular structure](data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%200%200'%3E%3C/svg%3E)
(3aR,6aR)-N-(4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)-1-methylhexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxamide
- CAS RN: 1353644-70-8
- Product Code: SSC-043586
-
(3aR,6aR)-1-Methyl-hexahydropyrrolo[3,4-b]pyrrole
- CAS RN: 1353644-77-5
- Product Code: SSC-043587
-
Chloro[(tricyclohexylphosphine)-2-(2′-aminobiphenyl)]palladium(II)
- CAS RN: 1353658-81-7
- Product Code: SSC-043591
-
“5,7,3′,4′-Tetrahydroxy-3-Methoxy-8,5′-diprenylflavone”
- CAS RN: 1353676-65-9
- Product Code: starshine_CAS1353676-65-9
- Purity/Analytical method: >99.0%
-
(1R)-3,3′-bis[3,5-bis(1,1-dimethylethyl)-4-methoxyphenyl]-[1,1′-Binaphthalene]-2,2′-diol
- CAS RN: 1353682-93-5
- Product Code: SSC-043596
-
4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(methylsulfonyl)pyridine
- CAS RN: 1353745-98-8
- Product Code: SSC-043604
![CAS 1353644-70-8 (3aR,6aR)-N-(4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)-1-methylhexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxamide molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1353644-70-8.gif)
![CAS 1353644-77-5 (3aR,6aR)-1-Methyl-hexahydropyrrolo[3,4-b]pyrrole molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1353644-77-5.gif)
![CAS 1353658-81-7 Chloro[(tricyclohexylphosphine)-2-(2′-aminobiphenyl)]palladium(II) molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1353658-81-7.gif)
![CAS 1353682-93-5 (1R)-3,3′-bis[3,5-bis(1,1-dimethylethyl)-4-methoxyphenyl]-[1,1′-Binaphthalene]-2,2′-diol molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1353682-93-5.gif)
