CAS RN: 1350653-20-1
vericiguat
Product Availability
Choose a grade to view its available package options.
9 package records8 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260125 | 2mg / 5mg / 25mg / 100mg / 500mg | Confirm by inquiry | Shanghai | Inquiry |
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260506 | 100mg | In stock | Shanghai, Tianjin, Wuhan | Inquiry |
| Batchno.20250202 | 10g | In stock | Shanghai | Inquiry |
| Batchno.20260125 | 1g | In stock | Shanghai, Tianjin | Inquiry |
| Batchno.20250712 | 250mg | In stock | Shanghai, Shenzhen, Tianjin, Chengdu | Inquiry |
| Batchno.20250910 | 25g | Out of stock | Inquiry | |
| Batchno.20250709 | 2mg / 5mg / 25mg / 100mg | Confirm by inquiry | Shanghai, Shandong | Inquiry |
| Batchno.20250817 | 50mg | In stock | Shanghai | Inquiry |
| Batchno.20250305 | 5g | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS1350653-20-1
- Purity/Analytical Methods: >99.0%
1350653-20-1 / methyl N-[4,6-diamino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate
Basic Information
CAS
1350653-20-1
Multi CAS
No
Molecular Formula
C19H16F2N8O2
Molecular Weight
426.400000
Exact Mass
426.136428
SMILES
COC(=O)NC1=C(N=C(N=C1N)C2=NN(C3=C2C=C(C=N3)F)CC4=CC=CC=C4F)N
InChI
InChI=1S/C19H16F2N8O2/c1-31-19(30)25-14-15(22)26-17(27-16(14)23)13-11-6-10(20)7-24-18(11)29(28-13)8-9-4-2-3-5-12(9)21/h2-7H,8H2,1H3,(H,25,30)(H4,22,23,26,27)
InChIKey
QZFHIXARHDBPBY-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
31
Aromatic heavy atom count
21
Fraction Csp3
0.11
Rotatable bonds
4
H-bond acceptors
9
H-bond donors
3
Molar refractivity
108.87
TPSA
146.86
LogP / Solubility
WLOGP
2.56
MLOGP
2.28
XLogP3
1.5
Consensus LogP
2.11
Log S (ESOL)
-4.33
Class (ESOL)
Slightly soluble
Log S (Ali)
-4.9
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-5.03
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.51
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
No
Egan
No
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3
Safety & Transport
Pictogram(s)
Health Hazard
Signal
Danger
GHS Hazard Statements
H372 (94.7%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]
Precautionary Statement Codes
P260, P264, P270, P319, and P501
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