![CAS 134575-11-4 Tert-Butyl (((Meso-1R,5S,6S)-3-Benzyl-3-Azabicyclo[3.1.0]Hexan-6-Yl)Methyl)Carbamate molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/134575-11-4.gif)
CAS RN: 134575-11-4
Tert-Butyl (((Meso-1R,5S,6S)-3-Benzyl-3-Azabicyclo[3.1.0]Hexan-6-Yl)Methyl)Carbamate
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20250801 | 100mg / 250mg / 1g | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS134575-11-4
- Purity/Analytical Methods: >99.0%
134575-11-4 / tert-butyl N-[[(1S,5R)-3-benzyl-3-azabicyclo[3.1.0]hexan-6-yl]methyl]carbamate
Basic Information
CAS
134575-11-4
Multi CAS
No
Molecular Formula
C18H26N2O2
Molecular Weight
302.400000
Exact Mass
302.199428
SMILES
CC(C)(C)OC(=O)NCC1[C@H]2[C@@H]1CN(C2)CC3=CC=CC=C3
InChI
InChI=1S/C18H26N2O2/c1-18(2,3)22-17(21)19-9-14-15-11-20(12-16(14)15)10-13-7-5-4-6-8-13/h4-8,14-16H,9-12H2,1-3H3,(H,19,21)/t14?,15-,16+
InChIKey
PZLROGVCOKZEST-MQVJKMGUSA-N
Computed Properties
Structural Parameters
Heavy atom count
22
Aromatic heavy atom count
6
Fraction Csp3
0.61
Rotatable bonds
4
H-bond acceptors
3
H-bond donors
1
Molar refractivity
86.43
TPSA
41.57
LogP / Solubility
WLOGP
2.89
MLOGP
2.55
XLogP3
2.8
Consensus LogP
2.75
Log S (ESOL)
-3.47
Class (ESOL)
Poorly soluble
Log S (Ali)
-4.13
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.5
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.51
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
Yes
Synthetic Accessibility
3.5
Customers Also Viewed
-
![CAS 134575-12-5 Carbamic acid, (3-azabicyclo[3.1.0]hex-6-ylmethyl)-, 1,1-dimethylethyl ester molecular structure](data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%200%200'%3E%3C/svg%3E)
Carbamic acid, (3-azabicyclo[3.1.0]hex-6-ylmethyl)-, 1,1-dimethylethyl ester
- CAS RN: 134575-12-5
- Product Code: SSC-042421
-
exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-methanol
- CAS RN: 134575-14-7
- Product Code: SSC-042423
-
exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-carboxylic acid
- CAS RN: 134575-15-8
- Product Code: SSC-042424
-
Carbamic acid, 3-azabicyclo[3.1.0]hex-6-yl-, 1,1-dimethylethyl ester
- CAS RN: 134575-17-0
- Product Code: SSC-042425
-
(1R,5S,6r)-3-tert-butyl 6-ethyl 3-azabicyclo[3.1.0]hexane-3,6-dicarboxylate
- CAS RN: 134575-37-4
- Product Code: SSC-042426
-
(1R,5S,6s)-3-benzyl 6-ethyl 3-azabicyclo[3.1.0]hexane-3,6-dicarboxylate
- CAS RN: 134575-38-5
- Product Code: SSC-042427
![CAS 134575-12-5 Carbamic acid, (3-azabicyclo[3.1.0]hex-6-ylmethyl)-, 1,1-dimethylethyl ester molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/134575-12-5.gif)
![CAS 134575-14-7 exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-methanol molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/134575-14-7.gif)
![CAS 134575-15-8 exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-carboxylic acid molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/134575-15-8.gif)
![CAS 134575-17-0 Carbamic acid, 3-azabicyclo[3.1.0]hex-6-yl-, 1,1-dimethylethyl ester molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/134575-17-0.gif)
![CAS 134575-37-4 (1R,5S,6r)-3-tert-butyl 6-ethyl 3-azabicyclo[3.1.0]hexane-3,6-dicarboxylate molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/134575-37-4.gif)
![CAS 134575-38-5 (1R,5S,6s)-3-benzyl 6-ethyl 3-azabicyclo[3.1.0]hexane-3,6-dicarboxylate molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/134575-38-5.gif)