CAS RN: 1345675-25-3
E6446 (dihydrochloride)
Product Availability
Choose a grade to view its available package options.
14 package records14 with current stock4 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250828 | 1ml | In stock | Inquiry |
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250407 | 100mg | In stock | Shanghai | Inquiry |
| Batchno.20260406 | 10mg | In stock | Shanghai, Wuhan | Inquiry |
| Batchno.20250113 | 1g | In stock | Shanghai | Inquiry |
| Batchno.20251016 | 1mg | In stock | Shanghai, Wuhan | Inquiry |
| Batchno.20251013 | 250mg | In stock | Shanghai | Inquiry |
| Batchno.20251116 | 25mg | In stock | Shanghai | Inquiry |
| Batchno.20260525 | 2mg | In stock | Shanghai, Wuhan | Inquiry |
| Batchno.20250508 | 50mg | In stock | Shanghai, Wuhan | Inquiry |
| Batchno.20250825 | 5mg | In stock | Shanghai, Wuhan | Inquiry |
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20251029 | 2mg / 5mg / 25mg / 100mg / 250mg | Confirm by inquiry | Shanghai | Inquiry |
- Product code: SSC-042398
Historical Factory Record
Historical Supply Reference
This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
- Pack sizes on record: 1g
- Available purity: ≥95%
- Inventory rows with stock: 0
- Bulk packaging: confirmed by inquiry
Reference Pack Sizes
Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.
| Pack Size | Recorded Purity | Available Qty | Ship From | Inquiry |
|---|---|---|---|---|
| 1g | ≥95% | 0 Out of Stock | Hong Kong | Inquiry |
1345675-25-3 / 6-(3-pyrrolidin-1-ylpropoxy)-2-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-1,3-benzoxazole;dihydrochloride
Basic Information
CAS
1345675-25-3
Multi CAS
No
Molecular Formula
C27H37Cl2N3O3
Molecular Weight
522.500000
Exact Mass
521.221197
SMILES
C1CCN(C1)CCCOC2=CC=C(C=C2)C3=NC4=C(O3)C=C(C=C4)OCCCN5CCCC5.Cl.Cl
InChI
InChI=1S/C27H35N3O3.2ClH/c1-2-14-29(13-1)17-5-19-31-23-9-7-22(8-10-23)27-28-25-12-11-24(21-26(25)33-27)32-20-6-18-30-15-3-4-16-30;;/h7-12,21H,1-6,13-20H2;2*1H
InChIKey
DQOUZINBHKWGGM-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
35
Aromatic heavy atom count
15
Fraction Csp3
0.52
Rotatable bonds
11
H-bond acceptors
6
H-bond donors
2
Molar refractivity
145.51
TPSA
50.97
LogP / Solubility
WLOGP
6.07
MLOGP
5.38
XLogP3
6.07
Consensus LogP
5.84
Log S (ESOL)
-6.49
Class (ESOL)
Insoluble
Log S (Ali)
-8.23
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-9.41
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.6
Drug-likeness / Medicinal Chemistry
Lipinski
No
Ghose
No
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.17
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
3.5
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