CAS RN: 127-19-5

N,N-Dimethylacetamide

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  • Product code: SSC-034374
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Verified Factory Data

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  • Pack sizes on record: 25g, 100g, 500g, 1000g, 5000g, 25000g
  • Available purity: >99%
  • Inventory rows with stock: 5
  • Bulk packaging: confirmed by inquiry
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Available Pack Sizes & Stock

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Recorded sizes, purity and stock details for CAS 127-19-5
Pack Size Recorded Purity Available Qty Ship From Inquiry
25g >99% 5 In Stock Shenzhen Inquiry
100g >99% 5 In Stock Hong Kong Inquiry
500g >99% 5 In Stock Shenzhen Inquiry
1000g >99% 1 In Stock Hong Kong Inquiry
5000g >99% 1 In Stock Beijing Inquiry
25000g >99% 0 Out of Stock Beijing Inquiry

127-19-5 / N,N-dimethylacetamide

Standard CAS: 127-19-5 Multi CAS: No

Basic Information

CAS
127-19-5
Multi CAS
No
Molecular Formula
C4H9NO
Molecular Weight
87.120000
Exact Mass
87.068414
SMILES
CC(=O)N(C)C
InChI
InChI=1S/C4H9NO/c1-4(6)5(2)3/h1-3H3
InChIKey
FXHOOIRPVKKKFG-UHFFFAOYSA-N

Physical Properties

Melting Point
-4 °F (NTP, 1992) -4 °F (USCG, 1999) -18.59 °C -20 °C -4 °F
Boiling Point
329 to 331 °F at 760 mmHg (NTP, 1992) 331 °F at 760 mmHg (USCG, 1999) 163-165 °C 165 °C 329 °F
Density
0.943 at 68 °F (USCG, 1999) - Less dense than water; will float 0.937 (USCG, 1999) - Less dense than water; will float 0.9366 @ 25 °C/4 °C Relative density (water = 1): 0.94 0.94
Physical Description
Dimethylacetamide appears as a clear colorless liquid with a faint odor similar to ammonia. About the same density as water. Flash point 145 °F. Vapors heavier than air. May by toxic by skin absorption. May irritate eyes and skin. N,n-dimethyl acetamide solution (40% or less) is a colorless liquid with a slight ammonia-like odor. (USCG, 1999) Liquid; Water or Solvent Wet Solid; Dry Powder Colorless liquid with a weak, ammonia- or fish-like odor; [NIOSH] OILY COLOURLESS LIQUID WITH PUNGENT ODOUR.
Appearance
Liquid OILY Colorless liquid
State
Solid

Computed Properties

Structural Parameters

Heavy atom count
6
Fraction Csp3
0.75
H-bond acceptors
1
Molar refractivity
24.37
TPSA
20.31

LogP / Solubility

WLOGP
0.09
MLOGP
0.07
XLogP3
-0.8
Consensus LogP
-0.21
Log S (ESOL)
-0.44
Class (ESOL)
Very soluble
Log S (Ali)
-0.34
Class (Ali)
Very soluble
Log S (SILICOS-IT)
-0.3
Class (SILICOS-IT)
Very soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.18

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5

Safety & Transport

Pictogram(s)
Irritant Health Hazard Acute Toxic
Signal
Danger Warning
GHS Hazard Statements
H312: Harmful in contact with skin [Warning Acute toxicity, dermal] H332: Harmful if inhaled [Warning Acute toxicity, inhalation] H360D ***: May damage the unborn child [Danger Reproductive toxicity] H312+H332 (13.2%): Harmful in contact with skin or if inhaled [Warning Acute toxicity, dermal; acute toxicity, inhalation] H312 (99.4%): Harmful in contact with skin [Warning Acute toxicity, dermal]
Precautionary Statement Codes
P203, P261, P271, P280, P302+P352, P304+P340, P317, P318, P321, P362+P364, P405, and P501 P203, P261, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P317, P318, P321, P337+P317, P362+P364, P405, and P501 P203, P210, P260, P261, P264, P264+P265, P270, P271, P280, P304+P340, P305+P351+P338, P308+P316, P316, P318, P319, P321, P337+P317, P370+P378, P403, P403+P233, P405, and P501 P203, P280, P318, P405, and P501 P203, P260, P261, P264, P264+P265, P270, P271, P280, P304+P340, P305+P351+P338, P316, P317, P318, P319, P321, P337+P317, P403+P233, P405, and P501

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