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CAS 1207360-89-1 N-Ethyl-N’-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea molecular structure lightbox
CAS RN: 1207360-89-1

N-Ethyl-N’-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

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6 package records6 with current stock2 grade groups
Batch No.PackageAvailabilityInquiry
Batchno.20260228 100mg In stock Inquiry
Batchno.20251130 10mg In stock Inquiry
Batchno.20251126 25mg In stock Inquiry
Batchno.20260314 50mg In stock Inquiry
Batchno.20260520 5mg In stock Inquiry
Batch No.PackageAvailabilityInquiry
Batchno.20260417 1ml In stock Inquiry
  • Product code: SSC-021938
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.25g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1207360-89-1
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.25g ≥95% 0 Out of Stock Shanghai Inquiry

1207360-89-1 / 1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

GDC-0349 | 579255I6O9 | DTXSID40152996

Standard CAS: 1207360-89-1 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
1207360-89-1
Multi CAS
Yes
Molecular Formula
C24H32N6O3
Molecular Weight
452.500000
Exact Mass
452.253589
SMILES
CCNC(=O)NC1=CC=C(C=C1)C2=NC3=C(CCN(C3)C4COC4)C(=N2)N5CCOC[C@@H]5C
InChI
InChI=1S/C24H32N6O3/c1-3-25-24(31)26-18-6-4-17(5-7-18)22-27-21-12-29(19-14-33-15-19)9-8-20(21)23(28-22)30-10-11-32-13-16(30)2/h4-7,16,19H,3,8-15H2,1-2H3,(H2,25,26,31)/t16-/m0/s1
InChIKey
RGJOJUGRHPQXGF-INIZCTEOSA-N
Synonyms
GDC-0349 579255I6O9 DTXSID40152996 RefChem:922128 DTXCID6075487

Computed Properties

Structural Parameters

Heavy atom count
33
Aromatic heavy atom count
12
Fraction Csp3
0.54
Rotatable bonds
5
H-bond acceptors
7
H-bond donors
2
Molar refractivity
126.51
TPSA
91.85

LogP / Solubility

WLOGP
2.27
MLOGP
2.03
XLogP3
1.4
Consensus LogP
1.9
Log S (ESOL)
-4.01
Class (ESOL)
Slightly soluble
Log S (Ali)
-4.91
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-5.08
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.87

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
4

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