CAS RN: 120685-11-2
Midostaurin
Product Availability
Choose a grade to view its available package options.
10 package records9 with current stock3 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260526 | 100mg / 250mg | Confirm by inquiry | Shanghai | Inquiry |
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250327 | 100mg | In stock | Shanghai | Inquiry |
| Batchno.20251109 | 100mg / 250mg / 1g | Confirm by inquiry | Shanghai, Shandong | Inquiry |
| Batchno.20260219 | 1g | In stock | Shanghai | Inquiry |
| Batchno.20250113 | 250mg | In stock | Shanghai, Shenzhen, Wuhan | Inquiry |
| Batchno.20251211 | 50mg | In stock | Shanghai | Inquiry |
| Batchno.20260207 | 5g | In stock | Shanghai | Inquiry |
- Product code: SSC-021765
Historical Factory Record
Historical Supply Reference
This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
- Pack sizes on record: 1g
- Available purity: ≥97%
- Inventory rows with stock: 0
- Bulk packaging: confirmed by inquiry
Reference Pack Sizes
Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.
| Pack Size | Recorded Purity | Available Qty | Ship From | Inquiry |
|---|---|---|---|---|
| 1g | ≥97% | 0 Out of Stock | Shenzhen | Inquiry |
120685-11-2 / N-[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-N-methylbenzamide
DTXSID40923522 | HB0521 | N-[(5R,6S,7R,8S)-15-Hydroxy-7-methoxy-7,8-dimethyl-5,6,7,8-tetrahydro-13H-5,8-epoxy-4b,8a,14-triazadibenzo[b,h]cycloocta[1,2,3,4-jkl]cyclopenta[e]-as-indacen-6-yl]-N-methylbenzamide
Basic Information
CAS
120685-11-2
Multi CAS
Yes
Molecular Formula
C35H30N4O4
Molecular Weight
570.600000
Exact Mass
570.226705
SMILES
C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
InChI
InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m1/s1
InChIKey
BMGQWWVMWDBQGC-IIFHNQTCSA-N
Synonyms
DTXSID40923522
HB0521
N-[(5R,6S,7R,8S)-15-Hydroxy-7-methoxy-7,8-dimethyl-5,6,7,8-tetrahydro-13H-5,8-epoxy-4b,8a,14-triazadibenzo[b,h]cycloocta[1,2,3,4-jkl]cyclopenta[e]-as-indacen-6-yl]-N-methylbenzamide
Physical Properties
Melting Point
235-260
Computed Properties
Structural Parameters
Heavy atom count
43
Aromatic heavy atom count
26
Fraction Csp3
0.26
Rotatable bonds
3
H-bond acceptors
6
H-bond donors
1
Molar refractivity
165.12
TPSA
77.73
LogP / Solubility
WLOGP
5.91
MLOGP
5.24
XLogP3
4.8
Consensus LogP
5.32
Log S (ESOL)
-7.35
Class (ESOL)
Insoluble
Log S (Ali)
-8.5
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-8.63
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.01
Drug-likeness / Medicinal Chemistry
Lipinski
No
Ghose
No
Veber
Yes
Egan
No
Muegge
No
Bioavailability score
0.17
Leadlikeness
No
Synthetic Accessibility
10
Safety & Transport
Pictogram(s)
Irritant
Health Hazard
Environmental Hazard
Signal
Danger
GHS Hazard Statements
H302 (40%): Harmful if swallowed [Warning Acute toxicity, oral]
H319 (20%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (20%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
H360 (20%): May damage fertility or the unborn child [Danger Reproductive toxicity]
H360Df (20%): May damage the unborn child; Suspected of damaging fertility [Danger Reproductive toxicity]
Precautionary Statement Codes
P203, P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P304+P340, P305+P351+P338, P318, P319, P330, P337+P317, P391, P403+P233, P405, and P501
Customers Also Viewed
-
5-Quinolinecarboxylic acid, 7,8-dihydro-6-hydroxy-2-Methoxy-, Methyleste
- CAS RN: 120686-00-2
- Product Code: starshine_CAS120686-00-2
- Purity/Analytical method: >99.0%
-
Spiro[1,3-dioxolane-2,6′(2’H)-quinolin]-2′-one, 1′,5′,7′,8′-tetrahydro-
- CAS RN: 120686-08-0
- Product Code: SSC-021766
-
-
-
-
3-Pyridineacetaldehyde,alpha,alpha-dimethyl-(9CI)
- CAS RN: 120690-79-1
- Product Code: SSC-021779
![CAS 120686-08-0 Spiro[1,3-dioxolane-2,6′(2’H)-quinolin]-2′-one, 1′,5′,7′,8′-tetrahydro- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/120686-08-0.gif)
