[email protected]
CAS 1206-62-8 8-Chloro-5-methoxy-2-methylquinolin-4-ol molecular structure lightbox
CAS RN: 1206-62-8

8-Chloro-5-methoxy-2-methylquinolin-4-ol

Product Availability

Choose a grade to view its available package options.

1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20251121 100mg / 250mg / 1g Out of stock 5-7 business days Inquiry
  • Product code: starshine_CAS1206-62-8
  • Purity/Analytical Methods: >99.0%
GET A QUOTE

1206-62-8 / 8-chloro-5-methoxy-2-methyl-1H-quinolin-4-one

8-Chloro-5-methoxy-2-methylquinolin-4-ol | 8-Chloro-5-methoxy-2-methyl-4-quinolinol | 8-Chloro-4-hydroxy-5-methoxy-2-methylquinoline

Standard CAS: 1206-62-8 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
1206-62-8
Multi CAS
No
Molecular Formula
C11H10ClNO2
Molecular Weight
223.650000
Exact Mass
223.040006
SMILES
CC1=CC(=O)C2=C(C=CC(=C2N1)Cl)OC
InChI
InChI=1S/C11H10ClNO2/c1-6-5-8(14)10-9(15-2)4-3-7(12)11(10)13-6/h3-5H,1-2H3,(H,13,14)
InChIKey
WQKSTGUXOLWBPE-UHFFFAOYSA-N
Synonyms
8-Chloro-5-methoxy-2-methylquinolin-4-ol 8-Chloro-5-methoxy-2-methyl-4-quinolinol 8-Chloro-4-hydroxy-5-methoxy-2-methylquinoline MFCD12675058 8-Chloro-5-methoxy-2-methylquinolin-4(1H)-one

Computed Properties

Structural Parameters

Heavy atom count
15
Aromatic heavy atom count
10
Fraction Csp3
0.18
Rotatable bonds
1
H-bond acceptors
2
H-bond donors
1
Molar refractivity
60.87
TPSA
42.09

LogP / Solubility

WLOGP
2.5
MLOGP
2.2
XLogP3
2.5
Consensus LogP
2.4
Log S (ESOL)
-3.23
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.2
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.31
Class (SILICOS-IT)
Poorly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.31

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5

Customers Also Viewed

Get In Touch

Contact Us