CAS RN: 1204669-58-8
Epacadostat (INCB024360)
Product Availability
Choose a grade to view its available package options.
19 package records16 with current stock3 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250603 | 1mg / 10mg / 100mg / 500mg / 1g | Confirm by inquiry | Shanghai, Shandong, Chongqing, Guangdong | Inquiry |
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260519 | 100mg | In stock | Shanghai, Shenzhen | Inquiry |
| Batchno.20250312 | 10g | Out of stock | Inquiry | |
| Batchno.20260331 | 10mg | In stock | Shanghai | Inquiry |
| Batchno.20250309 | 1g | In stock | Shanghai | Inquiry |
| Batchno.20260630 | 1mg | In stock | Shanghai | Inquiry |
| Batchno.20260112 | 250mg | In stock | Shanghai, Shenzhen, Tianjin, Wuhan, Chengdu | Inquiry |
| Batchno.20260528 | 2mg | In stock | Shanghai | Inquiry |
| Batchno.20250320 | 50mg | In stock | Shanghai | Inquiry |
| Batchno.20250814 | 5g | In stock | Shanghai | Inquiry |
| Batchno.20250606 | 5mg | In stock | Shanghai | Inquiry |
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250522 | 100mg | In stock | Inquiry | |
| Batchno.20250213 | 10mg | In stock | Inquiry | |
| Batchno.20260429 | 1g | Out of stock | Inquiry | |
| Batchno.20250126 | 250mg | In stock | Inquiry | |
| Batchno.20250822 | 25mg | Out of stock | Inquiry | |
| Batchno.20250424 | 500mg | In stock | Inquiry | |
| Batchno.20260420 | 50mg | In stock | Inquiry | |
| Batchno.20251231 | 5mg | In stock | Inquiry |
- Product code: SSC-021483
Historical Factory Record
Historical Supply Reference
This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
- Pack sizes on record: 0.1g, 0.25g, 1g
- Available purity: >98%
- Inventory rows with stock: 0
- Bulk packaging: confirmed by inquiry
Reference Pack Sizes
Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.
1204669-58-8 / N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboximidamide
INCB24360 | RefChem:923372 | Epacadostat
Basic Information
CAS
1204669-58-8
Multi CAS
Yes
Molecular Formula
C11H13BrFN7O4S
Molecular Weight
438.240000
Exact Mass
436.991710
SMILES
C1=CC(=C(C=C1N=C(C2=NON=C2NCCNS(=O)(=O)N)NO)Br)F
InChI
InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23)
InChIKey
FBKMWOJEPMPVTQ-UHFFFAOYSA-N
Synonyms
INCB24360
RefChem:923372
Epacadostat
IDO inhibitor 1
INCB-024360
Computed Properties
Structural Parameters
Heavy atom count
25
Aromatic heavy atom count
11
Fraction Csp3
0.18
Rotatable bonds
7
H-bond acceptors
8
H-bond donors
5
Molar refractivity
89.12
TPSA
167.76
LogP / Solubility
WLOGP
0.23
MLOGP
0.23
XLogP3
0.8
Consensus LogP
0.42
Log S (ESOL)
-2.57
Class (ESOL)
Moderately soluble
Log S (Ali)
-3.32
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.54
Class (SILICOS-IT)
Poorly soluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-5.23
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
2.5
Safety & Transport
Pictogram(s)
Irritant
Signal
Warning
GHS Hazard Statements
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
Precautionary Statement Codes
P264, P270, P301+P317, P330, and P501
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Sulfamide,N-[2-[[4-[4-(3-bromo-4-fluorophenyl)-4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl]-1,2,5-oxadiazol-3-yl]amino]ethyl]-
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Butanoic acid, 4,4′-[[(1,1-dimethylethoxy)carbonyl]imino]bis-
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- Purity/Analytical method: >99.0%
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