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CAS 120014-06-4 Donepezil molecular structure lightbox
CAS RN: 120014-06-4

Donepezil

Product Availability

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9 package records9 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250423 100g In stock Shanghai, Shenzhen Inquiry
Batchno.20260207 10g In stock Shanghai, Shenzhen Inquiry
Batchno.20251028 1g In stock Shanghai, Shenzhen, Tianjin, Wuhan, Chengdu Inquiry
Batchno.20250829 25g In stock Shanghai Inquiry
Batchno.20260420 25mg / 100mg / 1g / 5g / 25g / 100g / 500g Confirm by inquiry Shanghai, Shandong, Hebei, Guangdong Inquiry
Batchno.20250613 5g In stock Shanghai, Shenzhen, Tianjin Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20251017 100mg In stock Inquiry
Batchno.20260302 1g In stock Inquiry
Batchno.20250618 25mg In stock Inquiry
  • Product code: SSC-020827
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 5g
  • Available purity: ≥97%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 120014-06-4
Pack Size Recorded Purity Available Qty Ship From Inquiry
5g ≥97% 0 Out of Stock Beijing Inquiry

120014-06-4 / 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one

donepezil | donepezilo | Donaz

Standard CAS: 120014-06-4 Multi CAS: Yes
Basic Information Physical Properties Computed Properties Safety & Transport

Basic Information

CAS
120014-06-4
Multi CAS
Yes
Molecular Formula
C24H29NO3
Molecular Weight
379.500000
Exact Mass
379.214744
SMILES
COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC
InChI
InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3
InChIKey
ADEBPBSSDYVVLD-UHFFFAOYSA-N
Synonyms
donepezil donepezilo Donaz donepezilum Domepezil

Physical Properties

Melting Point
223-227
Physical Description
Solid
State
Solid
Storage Conditions
Store at 20 to 25 °C (68 to 77 °F)

Computed Properties

Structural Parameters

Heavy atom count
28
Aromatic heavy atom count
12
Fraction Csp3
0.46
Rotatable bonds
6
H-bond acceptors
4
Molar refractivity
110.13
TPSA
38.77

LogP / Solubility

WLOGP
4.36
MLOGP
3.86
XLogP3
4.3
Consensus LogP
4.17
Log S (ESOL)
-4.86
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.82
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-6.47
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.94

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5

Safety & Transport

Pictogram(s)
Acute Toxic Irritant
Signal
Danger
GHS Hazard Statements
H300 (88.9%): Fatal if swallowed [Danger Acute toxicity, oral] H302 (11.1%): Harmful if swallowed [Warning Acute toxicity, oral] H315 (11.1%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (22.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (11.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes
P261, P264, P264+P265, P270, P271, P273, P280, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

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