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CAS 1191911-27-9 CZC-54252 molecular structure lightbox
CAS RN: 1191911-27-9

CZC-54252

Product Availability

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13 package records12 with current stock4 grade groups
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20260422 5mg / 10mg / 25mg / 100mg / 250mg Confirm by inquiry Shanghai 5-7 business days Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20260503 100mg In stock Inquiry
Batchno.20250626 250mg Out of stock Inquiry
Batchno.20260103 25mg In stock Inquiry
Batchno.20250224 5mg In stock Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250206 1ml In stock Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250620 100mg In stock Shanghai Inquiry
Batchno.20260324 10mg In stock Shanghai Inquiry
Batchno.20250405 1mg In stock Shanghai Inquiry
Batchno.20250828 250mg In stock Shanghai Inquiry
Batchno.20260609 25mg In stock Shanghai, Wuhan Inquiry
Batchno.20250203 50mg In stock Shanghai, Shenzhen Inquiry
Batchno.20260509 5mg In stock Shanghai Inquiry
  • Product code: SSC-019659
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.25g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1191911-27-9
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.25g ≥95% 0 Out of Stock Beijing Inquiry

1191911-27-9 / N-[2-[[5-chloro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl]methanesulfonamide

CZC-54252 | N-(2-((5-Chloro-2-((2-methoxy-4-morpholinophenyl)amino)pyrimidin-4-yl)amino)phenyl)methanesulfonamide | N-{2-[(5-chloro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide

Standard CAS: 1191911-27-9 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
1191911-27-9
Multi CAS
Yes
Molecular Formula
C22H25ClN6O4S
Molecular Weight
505.000000
Exact Mass
504.134652
SMILES
COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)Cl
InChI
InChI=1S/C22H25ClN6O4S/c1-32-20-13-15(29-9-11-33-12-10-29)7-8-19(20)26-22-24-14-16(23)21(27-22)25-17-5-3-4-6-18(17)28-34(2,30)31/h3-8,13-14,28H,9-12H2,1-2H3,(H2,24,25,26,27)
InChIKey
CLGWUCNXOBLWFM-UHFFFAOYSA-N
Synonyms
CZC-54252 N-(2-((5-Chloro-2-((2-methoxy-4-morpholinophenyl)amino)pyrimidin-4-yl)amino)phenyl)methanesulfonamide N-{2-[(5-chloro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide MFCD26401527 C22H25ClN6O4S

Computed Properties

Structural Parameters

Heavy atom count
34
Aromatic heavy atom count
18
Fraction Csp3
0.27
Rotatable bonds
8
H-bond acceptors
9
H-bond donors
3
Molar refractivity
134.54
TPSA
117.71

LogP / Solubility

WLOGP
3.83
MLOGP
3.41
XLogP3
3.3
Consensus LogP
3.51
Log S (ESOL)
-5.25
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.47
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.08
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.08

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3

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