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CAS 1190315-74-2 4-Chloro-5-fluoro-7-aza-2-oxindole molecular structure lightbox
CAS RN: 1190315-74-2

4-Chloro-5-fluoro-7-aza-2-oxindole

Product Availability

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1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20260403 100mg / 250mg / 500mg Out of stock 1 business days Inquiry
  • Product code: SSC-019369
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 1g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1190315-74-2
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g ≥95% 0 Out of Stock Shanghai Inquiry

1190315-74-2 / 4-chloro-5-fluoro-1,3-dihydropyrrolo[2,3-b]pyridin-2-one

4-CHLORO-5-FLUORO-7-AZA-2-OXINDOLE | 4-CHLORO-5-FLUORO-1H,2H,3H-PYRROLO[2,3-B]PYRIDIN-2-ONE | 4-Chloro-5-fluoro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one

Standard CAS: 1190315-74-2 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
1190315-74-2
Multi CAS
No
Molecular Formula
C7H4ClFN2O
Molecular Weight
186.570000
Exact Mass
185.999619
SMILES
C1C2=C(C(=CN=C2NC1=O)F)Cl
InChI
InChI=1S/C7H4ClFN2O/c8-6-3-1-5(12)11-7(3)10-2-4(6)9/h2H,1H2,(H,10,11,12)
InChIKey
AFHGYJFHZMMUJA-UHFFFAOYSA-N
Synonyms
4-CHLORO-5-FLUORO-7-AZA-2-OXINDOLE 4-CHLORO-5-FLUORO-1H,2H,3H-PYRROLO[2,3-B]PYRIDIN-2-ONE 4-Chloro-5-fluoro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one MFCD12962827 2H-Pyrrolo[2,3-b]pyridin-2-one, 4-chloro-5-fluoro-1,3-dihydro-

Computed Properties

Structural Parameters

Heavy atom count
12
Aromatic heavy atom count
6
Fraction Csp3
0.14
H-bond acceptors
2
H-bond donors
1
Molar refractivity
41.54
TPSA
41.99

LogP / Solubility

WLOGP
1.37
MLOGP
1.2
XLogP3
0.8
Consensus LogP
1.12
Log S (ESOL)
-2.23
Class (ESOL)
Moderately soluble
Log S (Ali)
-2.08
Class (Ali)
Moderately soluble
Log S (SILICOS-IT)
-2.01
Class (SILICOS-IT)
Moderately soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.89

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5

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