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CAS 1190094-64-4 OSI-754 molecular structure lightbox
CAS RN: 1190094-64-4

OSI-754

Product Availability

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5 package records2 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250815 100mg In stock Shanghai Inquiry
Batchno.20260213 250mg Out of stock Inquiry
Batchno.20250409 25mg Out of stock Inquiry
Batchno.20260418 25mg / 100mg Out of stock 8-10 business days Inquiry
Batchno.20250712 50mg In stock Shanghai Inquiry
  • Product code: SSC-019281
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.1g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1190094-64-4
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.1g ≥95% 0 Out of Stock Shenzhen Inquiry

1190094-64-4 / 6-[(R)-(4-chlorophenyl)-hydroxy-(3-methylimidazol-4-yl)methyl]-4-(3-ethynylphenyl)-1-methylquinolin-2-one

LNK754 | (Rac)-CP-609754 | 6-((4-chlorophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-ethynylphenyl)-1-methylquinolin-2(1H)-one

Standard CAS: 1190094-64-4 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
1190094-64-4
Multi CAS
Yes
Molecular Formula
C29H22ClN3O2
Molecular Weight
480.000000
Exact Mass
479.140055
SMILES
CN1C=NC=C1[C@@](C2=CC=C(C=C2)Cl)(C3=CC4=C(C=C3)N(C(=O)C=C4C5=CC=CC(=C5)C#C)C)O
InChI
InChI=1S/C29H22ClN3O2/c1-4-19-6-5-7-20(14-19)24-16-28(34)33(3)26-13-10-22(15-25(24)26)29(35,27-17-31-18-32(27)2)21-8-11-23(30)12-9-21/h1,5-18,35H,2-3H3/t29-/m1/s1
InChIKey
JAHDAIPFBPPQHQ-GDLZYMKVSA-N
Synonyms
LNK754 (Rac)-CP-609754 6-((4-chlorophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-ethynylphenyl)-1-methylquinolin-2(1H)-one orb1707059 SCHEMBL1644297

Computed Properties

Structural Parameters

Heavy atom count
35
Aromatic heavy atom count
27
Fraction Csp3
0.1
Rotatable bonds
4
H-bond acceptors
5
H-bond donors
1
Molar refractivity
139.32
TPSA
60.05

LogP / Solubility

WLOGP
4.86
MLOGP
4.31
XLogP3
4
Consensus LogP
4.39
Log S (ESOL)
-6.18
Class (ESOL)
Insoluble
Log S (Ali)
-7
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.29
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.2

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
4

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