CAS RN: 1187594-09-7
Baricitinib
Product Availability
Choose a grade to view its available package options.
16 package records15 with current stock3 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20251021 | 100mg | In stock | Shanghai, Shenzhen | Inquiry |
| Batchno.20250714 | 10mg | In stock | Shanghai | Inquiry |
| Batchno.20250902 | 1g | In stock | Shanghai, Shenzhen, Tianjin | Inquiry |
| Batchno.20260127 | 1mg | In stock | Shanghai | Inquiry |
| Batchno.20260317 | 250mg | In stock | Shanghai, Shenzhen, Tianjin | Inquiry |
| Batchno.20260101 | 25g | Out of stock | Inquiry | |
| Batchno.20260402 | 2mg | In stock | Shanghai | Inquiry |
| Batchno.20260602 | 50mg | In stock | Shanghai | Inquiry |
| Batchno.20251226 | 5g | In stock | Shanghai, Shenzhen | Inquiry |
| Batchno.20250622 | 5mg | In stock | Shanghai | Inquiry |
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260619 | 1ml | In stock | Inquiry |
- Product code: starshine_CAS1187594-09-7
- Purity/Analytical Methods: >99.0%
1187594-09-7 / 2-[1-ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile
Baricitinib | olumiant | LY3009104
Basic Information
CAS
1187594-09-7
Multi CAS
Yes
Molecular Formula
C16H17N7O2S
Molecular Weight
371.400000
Exact Mass
371.116444
SMILES
CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
InChI
InChI=1S/C16H17N7O2S/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20)
InChIKey
XUZMWHLSFXCVMG-UHFFFAOYSA-N
Synonyms
Baricitinib
olumiant
LY3009104
INCB028050
INCB 028050
Computed Properties
Structural Parameters
Heavy atom count
26
Aromatic heavy atom count
14
Fraction Csp3
0.38
Rotatable bonds
5
H-bond acceptors
7
H-bond donors
1
Molar refractivity
94.35
TPSA
120.56
LogP / Solubility
WLOGP
1.1
MLOGP
0.98
XLogP3
-0.5
Consensus LogP
0.53
Log S (ESOL)
-2.9
Class (ESOL)
Moderately soluble
Log S (Ali)
-3.4
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.58
Class (SILICOS-IT)
Poorly soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-4.21
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3
Safety & Transport
Pictogram(s)
Irritant
Health Hazard
Environmental Hazard
Signal
Danger
GHS Hazard Statements
H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
H335 (16.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
H360 (66.7%): May damage fertility or the unborn child [Danger Reproductive toxicity]
H360FD (16.7%): May damage fertility; May damage the unborn child [Danger Reproductive toxicity]
H372 (16.7%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]
Precautionary Statement Codes
P203, P260, P261, P264, P270, P271, P273, P280, P301+P317, P304+P340, P318, P319, P330, P391, P403+P233, P405, and P501
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![CAS 1187595-88-5 4-(1-(1-ethoxyethyl)-1H-pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1187595-88-5.gif)
